Evidence map›Paper›PMID 27702424›Full record

Observational studyPublic health nutrition2017

Duration of periconceptional folic acid supplementation in women booking for antenatal care.

Shona Cawley, Laura Mullaney, Rachel Kennedy, Maria Farren, Daniel McCartney, Michael J Turner

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Public health nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shona Cawley1School of Biological Sciences,Dublin Institute of Technology,Dublin,Republic of Ireland.
Laura Mullaney1School of Biological Sciences,Dublin Institute of Technology,Dublin,Republic of Ireland.
Rachel Kennedy1School of Biological Sciences,Dublin Institute of Technology,Dublin,Republic of Ireland.
Maria Farren2UCD Centre for Human Reproduction,Coombe Women and Infants University Hospital,Dublin,Republic of Ireland.
Daniel McCartney1School of Biological Sciences,Dublin Institute of Technology,Dublin,Republic of Ireland.
Michael J Turner2UCD Centre for Human Reproduction,Coombe Women and Infants University Hospital,Dublin,Republic of Ireland.
Coombe Women & Infants University Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo provide accurate estimates of the commencement time, duration and dosage of folic acid (FA) supplementation taken by Irish women in the periconceptional period. The study also aimed to establish the factors associated with optimal FA supplementation practices.

designCross-sectional observational study. Women's clinical and sociodemographic details were computerised. Maternal weight and height were measured before calculating BMI. Detailed FA supplementation questionnaires were completed under the supervision of a trained researcher.

settingA large university maternity hospital, Republic of Ireland, January 2014-April 2016. SUBJECTS: Women (n 856) recruited at their convenience in the first trimester.

resultsWhile almost all of the women (97 %) were taking FA at enrolment, only one in four women took FA for at least 12 weeks preconceptionally (n 208). Among the 44 % of women who were supplementing with FA preconceptionally, 44 % (162/370) reported taking FA for less than the 12 weeks required to achieve optimal red-blood-cell folate levels for prevention of neural tube defects. On multivariate analysis, only planned pregnancy and nulliparity were associated with taking FA for at least 12 weeks preconceptionally. Among women who only took FA postconceptionally, almost two-thirds commenced it after day 28 of their pregnancy when the neural tube had already closed.

conclusionsAs the timing of FA was suboptimal both before and after conception, we recommend that current national FA guidelines need to be reviewed.

Indexed as

AdultCross-Sectional StudiesDietary SupplementsFemaleFolic AcidHospitals, MaternityHumansIrelandPreconception CarePregnancyPrenatal CareSurveys and QuestionnairesTime FactorsVitamin B ComplexFolic AcidVitamin B ComplexCongenital malformationsNeural tube defectsPericonceptional folic acid

Identifiers

PMID27702424
PMCPMC10261302
OpenAlexW2528975169

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.