Evidence map›Paper›PMID 27701741›Full record

ArticleEuropean journal of immunology2016

Type I IFN signaling facilitates the development of IL-10-producing effector CD8

Li Jiang, Shuyu Yao, Su Huang, Jeffrey Wright, Thomas J Braciale, Jie Sun

Open access · bronzeAbstract read
In one paragraph

Article in European journal of immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 47 citations in OpenAlex.

  1. Restricted MHC-II trafficking inbioRxiv : the preprint server for biology · 2026
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  5. Cytotoxic T Cells: Kill, Memorize, and Mask to Maintain Immune Homeostasis.International journal of molecular sciences · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Frontiers in cellular and infection microbiology · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Silent Infection of B and CD8Journal of virology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Li JiangDepartment of Pediatrics, Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.
Shuyu YaoDepartment of Pediatrics, Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.
Su HuangDepartment of Pediatrics, Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.
Jeffrey WrightBeirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.
Thomas J BracialeBeirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.
Jie SunDepartment of Pediatrics, Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.
Indiana University School of MedicineCarter Center · USIndiana University – Purdue University Indianapolis · US

Funding

Regulation of CD8+ T cell responses via liver NK-DC crosstalkU19AI083024 · NIAID · UNIVERSITY OF VIRGINIA · PI BRACIALE, THOMAS J · 2009 to 2013
$8.1M
Molecular regulation of protective CD8 immunity against influenza infectionR01AI112844 · NIAID · UNIVERSITY OF VIRGINIA · PI SUN, JIE · 2015 to 2024
$4.5M
Regulation of pulmonary anti-viral immunity in normal and obese hostsR01HL126647 · NHLBI · MAYO CLINIC ROCHESTER · PI SUN, JIE · 2015 to 2019
$1.9M
Simultaneously boosting both humoral and cellular immunity following vaccinationR01AG047156 · NIA · MAYO CLINIC ROCHESTER · PI SUN, JIE · 2015 to 2019
$1.6M
Targeting macrophage Bcl6 to enhance innate resistance to influenzaR21AI119612 · NIAID · MAYO CLINIC ROCHESTER · PI SUN, JIE · 2015 to 2016
$446k
Regulating pulmonary inflammation by type I IFN signaling in neutrophils during iR21AI099753 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI SUN, JIE · 2012 to 2013
$429k
NHLBI NIH HHS R01 HL126647NIAID NIH HHS R01 AI112844NIAID NIH HHS R21 AI099753NIAID NIH HHS R21 AI119612NIAID NIH HHS U19 AI083024NIA NIH HHS R01 AG047156
6 · The paper itself

Abstract

Recent evidence has suggested that IL-10-producing effector CD8

Indexed as

AnimalsCD8-Positive T-LymphocytesCells, CulturedDendritic CellsHumansInfluenza, HumanInterferon Type IInterleukin-10LungLymphocyte ActivationMiceMice, Inbred C57BLOrthomyxoviridaeOrthomyxoviridae InfectionsReceptor, Interferon alpha-betaSignal TransductionIfnar1 protein, mouseInterferon Type IInterleukin-10Receptor, Interferon alpha-betaStat2 protein, mouseSTAT2 Transcription FactorCD8+ T cellsIL-10IL-27InfluenzaType I IFN

Identifiers

PMID27701741
PMCPMC5184847
OpenAlexW2528896652

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.