Evidence map›Paper›PMID 27701733›Full record

ArticleEuropean journal of immunology2016

Antigen presentation by B cells guides programing of memory CD4

Natasha Dubois Cauwelaert, Susan L Baldwin, Mark T Orr, Anthony L Desbien, Emily Gage, Kimberly A Hofmeyer, Rhea N Coler

Abstract read
In one paragraph

Article in European journal of immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Natasha Dubois CauwelaertInfectious Disease Research Institute, Seattle, WA, USA.
Susan L BaldwinInfectious Disease Research Institute, Seattle, WA, USA.
Mark T OrrInfectious Disease Research Institute, Seattle, WA, USA.
Anthony L DesbienInfectious Disease Research Institute, Seattle, WA, USA.
Emily GageInfectious Disease Research Institute, Seattle, WA, USA.
Kimberly A HofmeyerInfectious Disease Research Institute, Seattle, WA, USA.
Rhea N ColerInfectious Disease Research Institute, Seattle, WA, USA.
Infectious Disease Research Institute · USUniversity of Washington · US

Funding

Development and Manufacture of Adjuvants for Vaccines Targeting MDR TuberculosisU01AI078054 · NIAID · ACCESS TO ADVANCED HEALTH INSTITUTE · PI COLER, RHEA N · 2008 to 2011
$6.2M
NIAID NIH HHS HHSN272200800045CNIAID NIH HHS U01 AI078054
6 · The paper itself

Abstract

The contribution of B cells to immunity against many infectious diseases is unquestionably important and well characterized. Here, we sought to determine the role of B cells in the induction of T-helper 1 (T

Indexed as

Antigen PresentationAdoptive TransferAnimalsB-LymphocytesCell DifferentiationCells, CulturedHumansImmunoglobulin mu-ChainsImmunologic FactorsImmunologic MemoryLymphocyte ActivationMiceMice, KnockoutTh1 CellsT-Lymphocyte SubsetsToll-Like Receptor 4Immunoglobulin mu-ChainsImmunologic FactorsTlr4 protein, mouseToll-Like Receptor 4Tuberculosis VaccinesB cells · T cells · μMT−/− mice · memory precursor effector cells · TLR4 agonist

Identifiers

PMID27701733
PMCPMC5172604
OpenAlexW2528793190

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.