ArticleBritish journal of cancer2016
Risk of hospitalisation and death due to bone fractures after breast cancer: a registry-based cohort study.
Article in British journal of cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- The effect of denosumab in breast cancer patients receiving adjuvant aromatase inhibitors: 36-month results.Journal of bone and mineral metabolism · 2021Trial
- Enhancing Timeliness and Compliance of Osteoporosis Care in Oncology: Evidence from a Dedicated Bone Health Service.Journal of clinical medicine · 2025Article
- Article
- Predictive value of frailty and nutritional risk screening for in-hospital complications in elderly hip fracture patients.Asia Pacific journal of clinical nutrition · 2025Article
- Bone Effects of Anti-Cancer Treatments in 2024.Calcified tissue international · 2025Review
- Differences in Physical Activity Recommendations, Levels of Physical Activity and Main Barriers to Exercise Between Spanish and Polish Cancer Patients.Healthcare (Basel, Switzerland) · 2025Article
- Gynecologic Care of Black Breast Cancer Survivors.Current breast cancer reports · 2024Article
- Physical therapist management and coordination of care to prevent pathological hip fracture from metastatic disease: a case report.Frontiers in rehabilitation sciences · 2024Article
- Article
- The impact of bone mineral density screening on incident fractures and healthcare resource utilization among postmenopausal breast cancer survivors treated with aromatase inhibitors.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022Article
- Bone fragility related to breast cancer treatment: The pivotal role of nurses in bone health program development, implementation, and testing.Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2022Article
- Article
- Chemotherapy-induced peripheral neuropathy increases nontraumatic fracture risk in breast cancer survivors.JBMR plus · 2021Article
- Cost-effectiveness of Tamoxifen, Aromatase Inhibitor, and Switch Therapy (Adjuvant Endocrine Therapy) for Breast Cancer in Hormone Receptor Positive Postmenopausal Women in India.Breast cancer (Dove Medical Press) · 2021Article
- Current practice patterns of osteoporosis treatment in cancer patients and effects of therapeutic interventions in a tertiary center.PloS one · 2021Article
- Real-world prevalence of potential drug-drug interactions involving oral antineoplastic agents: a population-based study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Article
- Management manual for cancer treatment-induced bone loss (CTIBL): position statement of the JSBMR.Journal of bone and mineral metabolism · 2020Article
- Association of Fat Body Mass With Vertebral Fractures in Postmenopausal Women With Early Breast Cancer Undergoing Adjuvant Aromatase Inhibitor Therapy.JAMA network open · 2019Article
- Exercise for managing cancer- and treatment-related side effects in older adults.Journal of geriatric oncology · 2018Review
- Management of Aromatase Inhibitor-Associated Bone Loss (AIBL) in postmenopausal women with hormone sensitive breast cancer: Joint position statement of the IOF, CABS, ECTS, IEG, ESCEO IMS, and SIOG.Journal of bone oncology · 2017Review
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10 authors.
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Abstract
backgroundBone fractures may have an impact on prognosis of breast cancer. The long-term risks of bone fracture in breast cancer patients have not been thoroughly studied.
methodsPoisson regression was used to investigate the incidence of hospitalisation due to bone fracture comparing women with and without breast cancer based on Swedish National registers. Cox regression was used to investigate the risk of being hospitalised with bone fracture, and subsequent risk of death, in a regional cohort of breast cancer patients.
resultsFor breast cancer patients, the 5-year risk of bone fracture hospitalisation was 4.8% and the 30-day risk of death following a bone fracture hospitalisation was 2.0%. Compared with the general population, breast cancer patients had incidence rate ratios of 1.25 (95% CI: 1.23-1.28) and 1.18 (95% CI: 1.14-1.22) for hospitalisation due to any bone fracture and hip fracture, respectively. These ratios remained significantly increased for 10 years. Comorbidities (Charlson Comorbidity Index ⩾1) were associated with the risk of being hospitalised with bone fracture. Women taking aromatase inhibitors were at an increased risk as compared with women taking tamoxifen (HR=1.48; 95% CI: 0.98-2.22). Breast cancer patients hospitalised for a bone fracture showed a higher risk of death (HR=1.83; 95% CI: 1.50-2.22) compared with those without bone fracture.
conclusionsWomen with a previous breast cancer diagnosis are at an increased risk of hospitalisation due to a bone fracture, particularly if they have other comorbidities.
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