Evidence map›Paper›PMID 27700226›Full record

ArticleRNA biology2016

LncRNAs: Bridging environmental sensing and gene expression.

Zachary T Beck, Zheng Xing, Elizabeth J Tran

Open access · bronzeAbstract read
In one paragraph

Article in RNA biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. eLife · 2023
    Article
  8. Review
  9. Article
  10. Review
  11. Natural temperature fluctuations promoteGenes & development · 2021
    Article
  12. The Expression of the Cancer-Associated lncRNAInternational journal of molecular sciences · 2021
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Zachary T Becka Department of Biochemistry , Purdue University , West Lafayette , IN , USA.
Zheng Xinga Department of Biochemistry , Purdue University , West Lafayette , IN , USA.
Elizabeth J Trana Department of Biochemistry , Purdue University , West Lafayette , IN , USA.
Purdue University West Lafayette · US

Funding

The Role of DEAD-box Proteins in Gene ExpressionR01GM097332 · NIGMS · PURDUE UNIVERSITY · PI TRAN, ELIZABETH J · 2011 to 2025
$4.1M
NIGMS NIH HHS R01 GM097332
6 · The paper itself

Abstract

The survival of all organisms is dependent on complex, coordinated responses to environmental cues. Non-coding RNAs have been identified as major players in regulation of gene expression, with recent evidence supporting roles for long non-coding (lnc)RNAs in both transcriptional and post-transcriptional control. Evidence from our laboratory shows that lncRNAs have the ability to form hybridized structures called R-loops with specific DNA target sequences in S. cerevisiae, thereby modulating gene expression. In this Point of View, we provide an overview of the nature of lncRNA-mediated control of gene expression in the context of our studies using the GAL gene cluster as a model for controlling the timing of transcription.

Indexed as

DNA, FungalFungal ProteinsGalactokinaseGene Expression Regulation, FungalNucleic Acid ConformationRNA, FungalRNA, Long NoncodingSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTrans-ActivatorsDNA, FungalFungal ProteinsGAL10 protein, S cerevisiaeGAL1 protein, S cerevisiaeGalactokinaseRNA, FungalRNA, Long NoncodingSaccharomyces cerevisiae ProteinsTrans-ActivatorsEnvironmentgene expressionhelicaselong non-codingmetabolismncRNAR-loops

Identifiers

PMID27700226
PMCPMC5207385
OpenAlexW2527678392

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.