Evidence map›Paper›PMID 27699845›Full record

ArticleInternational journal of geriatric psychiatry2017

Management of older adults with dementia who present to emergency services with neuropsychiatric symptoms.

Ryan M Silwanowicz, Donovan T Maust, Lisa S Seyfried, Claire Chiang, Claire Stano, Helen C Kales

Abstract read
In one paragraph

Article in International journal of geriatric psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Aggressive Behaviors in Alzheimer Disease and Mild Cognitive Impairment: Systematic Review and Meta-Analysis.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2019
    Pooled it
  2. Toward Precision Neuropsychiatry of Dementia: Neuropsychiatric Symptoms as Multidimensional Clinical Phenotypes.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2026
    Review
  3. A Novel Approach to Addressing Neuropsychiatric Symptoms in the UCSF Emergency Department: Code DICE.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Emergency Department Utilization among Underserved African American Older Adults in South Los Angeles.International journal of environmental research and public health · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ryan M SilwanowiczDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Donovan T MaustDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Lisa S SeyfriedDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Claire ChiangDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Claire StanoDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Helen C KalesDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA.

Funding

Preventable Hospitalization in Dementia: The Impact of Neuropsychiatric SymptomsK08AG048321 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MAUST, DONOVAN T · 2014 to 2017
$700k
NIA NIH HHS K08 AG048321
6 · The paper itself

Abstract

objectiveOur aim is to evaluate if and how neuropsychiatric symptoms (NPS) of dementia influence the management and disposition of older adults who present to emergency care settings.

methodsThis is a retrospective cohort study that involved the medical and psychiatric emergency departments of a tertiary academic medical center. Participants included patients ≥65 years of age with dementia who presented between 1 February 2012 and 16 July 2014 (n = 347). Subjects with documented NPS (n = 78) were compared with a group of subjects without documented NPS (n = 78) randomly selected from the overall group with dementia. The groups with and without NPS were compared on demographic, clinical, management, and disposition characteristics.

resultsPatients with NPS were more likely to have additional diagnostic testing performed and receive psychotropic medications including benzodiazepines and antipsychotics. Significantly fewer patients with NPS (59.0%) returned to their original setting from the emergency department than patients without NPS (76.9%). Among patients with NPS, those who had a motor disturbance were more likely to receive psychotropic medications than patients who did not have a motor disturbance. Depression/dysphoria, anxiety, disinhibition, irritability/lability, and motor disturbance were all associated with transfer from medical to psychiatric emergency department. Patients with depression/dysphoria or anxiety were more likely to be psychiatrically hospitalized.

conclusionsThere are significant differences in the management of dementia with and without NPS in the emergency room setting. Developing and implementing successful methods to manage NPS in the emergency department and outpatient setting could potentially lead to less emergent psychotropic administration and reduce hospitalizations. Copyright © 2016 John Wiley & Sons, Ltd.

Indexed as

AgedAged, 80 and overAntipsychotic AgentsDementiaEmergency Service, HospitalFemaleHospitalizationHospitals, PsychiatricHumansMaleMotor DisordersPsychotropic DrugsRetrospective StudiesAntipsychotic AgentsPsychotropic Drugsdementiaemergency departmentneuropsychiatric symptoms

Identifiers

PMID27699845
PMCPMC5378688

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.