Evidence map›Paper›PMID 27699844›Full record

ArticleMagnetic resonance in medicine2017

Specialized volumetric thermometry for improved guidance of MRgFUS in brain.

Michael Marx, Pejman Ghanouni, Kim Butts Pauly

Open access · bronzeAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 33 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Predicting ablation zones with multislice volumetric 2-D magnetic resonance thermal imaging.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2021
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Validation of hybrid angular spectrum acoustic and thermal modelling in phantoms.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2018
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Michael MarxDepartment of Radiology, Stanford University, Stanford, California, USA.
Pejman GhanouniDepartment of Radiology, Stanford University, Stanford, California, USA.
Kim Butts PaulyDepartment of Radiology, Stanford University, Stanford, California, USA.
Stanford University · US

Funding

MRI Methods for Guiding Focused Ultrasound in the BrainP01CA159992 · NCI · STANFORD UNIVERSITY · PI DANIEL, BRUCE L · 2011 to 2015
$8.2M
MR-guided Focused Ultrasound Neuromodulation of Deep Brain StructuresR01MH111825 · NIMH · STANFORD UNIVERSITY · PI BUTTS-PAULY, KIM · 2016 to 2019
$1.6M
NCI NIH HHS P01 CA159992NIMH NIH HHS R01 MH111825
6 · The paper itself

Abstract

purposeMR thermometry is critical for safe and effective transcranial focused ultrasound. The current single-slice MR thermometry sequence cannot achieve all desired treatment monitoring requirements. We propose an approach in which the imaging requirements of different aspects of treatment monitoring are met by optimizing multiple sequences.

methodsImaging requirements were determined for three stages of MR-guided focused ultrasound brain treatment: 1) focal spot localization, 2) focal spot monitoring, and 3) background monitoring. Multiple-echo spiral thermometry sequences were optimized for each set of requirements and then validated with in vivo signal-to-noise ratio measurements and with phantom heating experiments.

resultsEach of the proposed sequences obtained better precision than the current two-dimensional Fourier transform (2DFT) thermometry sequence. Five-slice focal spot localization achieved two-fold better resolution with 1.9-fold better precision but two-fold longer acquisition compared to 2DFT. Five-slice focal monitoring achieved 2.1-fold better precision with similar speed but 12% larger voxels than 2DFT. Full-brain background monitoring was demonstrated in both axial (7.1 s) and sagittal (11.4 s) orientations. Phantom heating time curves were consistent across all sequences after correcting for resolution.

conclusionMultiple-echo spiral imaging significantly improves MR thermometry efficiency, enabling multiple-slice monitoring. Optimizing multiple specialized sequences provides better performance than can be achieved by any single sequence. Magn Reson Med 78:508-517, 2017. © 2016 International Society for Magnetic Resonance in Medicine.

Indexed as

AlgorithmsBrainHigh-Intensity Focused Ultrasound AblationHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingPhantoms, ImagingSurgery, Computer-AssistedThermometryHIFUMR thermometrymultiple echomultiple slicespiral MRIvolumetric monitoring

Identifiers

PMID27699844
PMCPMC12393795
OpenAlexW2531153794

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.