Evidence map›Paper›PMID 27699641›Full record

ReviewClinical journal of gastroenterology2016

Recent trends and future directions for the medical treatment of ulcerative colitis.

Makoto Naganuma, Shinta Mizuno, Kosaku Nanki, Shinya Sugimoto, Takanori Kanai

Open access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Clinical journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Observational
  6. Analysis of the initial dose and reduction rate of corticosteroid for ulcerative colitis in clinical practice.JGH open : an open access journal of gastroenterology and hepatology · 2022
    Article
  7. Article
  8. Article
  9. Root Extract ofFrontiers in pharmacology · 2021
    Article
  10. Review
  11. Efficacy and Safety ofFrontiers in pharmacology · 2020
    Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Makoto NaganumaDepartment of Gastroenterology, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan. nagamakoto@z7.keio.jp.
Shinta MizunoDepartment of Gastroenterology, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
Kosaku NankiDepartment of Gastroenterology, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
Shinya SugimotoDepartment of Gastroenterology, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
Takanori KanaiDepartment of Gastroenterology, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
Keio University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, several medical treatments for ulcerative colitis (UC) have been developed, including 5-aminosalicylic acids (5-ASAs), corticosteroids, thiopurine, calcineurin inhibitors, and anti-tumor necrosis factor (TNF) α treatments. Treatment options including calcineurin inhibitors and anti-TNF treatment for refractory UC are discussed in this article. Furthermore, upcoming treatments are introduced, such as golimumab, vedolizumab, AJM300, tofacitinib. Budesonide foamwill be used as one treatment option in patients with distal colitis. Herbal medicine, such as Qing-Dai is also effective for active UC and may be useful for patients who are refractory to anti-TNFα treatments. In the near future, physicians will able to use many different treatments for UC patients. However, we should not forget 5-ASA and corticosteroids as the fundamental treatments for UC patients.

Indexed as

Antibodies, MonoclonalAntibodies, Monoclonal, HumanizedBudesonideCalcineurin InhibitorsColitis, UlcerativeDrugs, Chinese HerbalDrug Therapy, CombinationForecastingGastrointestinal AgentsGlucocorticoidsHumansPhenylalaninePiperidinesPyrimidinesPyrrolesQuinazolinonesAJM300Antibodies, MonoclonalAntibodies, Monoclonal, HumanizedBudesonideCalcineurin InhibitorsDrugs, Chinese HerbalGastrointestinal AgentsGlucocorticoidsgolimumabPhenylalaninePiperidinesPyrimidinesPyrrolesQingdai compoundQuinazolinonestofacitinibTumor Necrosis Factor-alphavedolizumabAnti-adhesion antibodyAnti-TNF treatmentsCalcineurin inhibitorsThe current treatment guideline for UCUlcerative colitis

Identifiers

PMID27699641
OpenAlexW2528207331

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.