ArticleAIDS and behavior2017
The Interaction of Risk Network Structures and Virus Natural History in the Non-spreading of HIV Among People Who Inject Drugs in the Early Stages of the Epidemic.
Article in AIDS and behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Review of Network Models for HIV Spread.Journal of acquired immune deficiency syndromes (1999) · 2025Pooled it
- A review of network simulation models of hepatitis C virus and HIV among people who inject drugs.The International journal on drug policy · 2021Review
- Immunization strategies in networks with missing data.PLoS computational biology · 2020Article
- Cost-effectiveness of Direct Antiviral Agents for Hepatitis C Virus Infection and a Combined Intervention of Syringe Access and Medication-assisted Therapy for Opioid Use Disorders in an Injection Drug Use Population.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020Article
- Social Networks of Substance-Using Populations: Key Issues and Promising New Approaches for HIV.Current HIV/AIDS reports · 2019Review
- Injection Partners, HCV, and HIV Status among Rural Persons Who Inject Drugs in Puerto Rico.Substance use & misuse · 2018Article
- Network Research Experiences in New York and Eastern Europe: Lessons for the Southern US in Understanding HIV Transmission Dynamics.Current HIV/AIDS reports · 2018Review
- Near Full-length Genomic Sequencing and Molecular Analysis of HIV-Infected Individuals in a Network-based Intervention (TRIP) in Athens, Greece: Evidence that Transmissions Occur More Frequently from those with High HIV-RNA.Current HIV research · 2018Article
- Pockets of HIV Non-infection Within Highly-Infected Risk Networks in Athens, Greece.Frontiers in microbiology · 2018Article
- Article
- "It Ruined My Life": The effects of the War on Drugs on people who inject drugs (PWID) in rural Puerto Rico.The International journal on drug policy · 2018Article
- Structural Sensitivity in HIV Modeling: A Case Study of Vaccination.Infectious Disease Modelling · 2017Article
- Needle acquisition patterns, network risk and social capital among rural PWID in Puerto Rico.Harm reduction journal · 2017Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
This article explores how social network dynamics may have reduced the spread of HIV-1 infection among people who inject drugs during the early years of the epidemic. Stochastic, discrete event, agent-based simulations are used to test whether a "firewall effect" can arise out of self-organizing processes at the actor level, and whether such an effect can account for stable HIV prevalence rates below population saturation. Repeated simulation experiments show that, in the presence of recurring, acute, and highly infectious outbreaks, micro-network structures combine with the HIV virus's natural history to reduce the spread of the disease. These results indicate that network factors likely played a significant role in the prevention of HIV infection within injection risk networks during periods of peak prevalence. They also suggest that social forces that disturb network connections may diminish the natural firewall effect and result in higher rates of HIV.
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Registered trials
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