Evidence map›Paper›PMID 27699593›Full record

ArticleDrug delivery and translational research2017

Biodegradable starch derivatives with tunable charge density-synthesis, characterization, and transfection efficiency.

Carolin Thiele, Brigitta Loretz, Claus-Michael Lehr

Abstract read
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In one paragraph

Article in Drug delivery and translational research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Carolin ThieleDepartment of Drug Delivery, Helmholtz-Institute for Pharmaceutical Research Saarland, Helmholtz-Centre for Infection Research Braunschweig, Saarland University, Campus, Building E8.1, 66123, Saarbrücken, Germany.
Brigitta LoretzDepartment of Drug Delivery, Helmholtz-Institute for Pharmaceutical Research Saarland, Helmholtz-Centre for Infection Research Braunschweig, Saarland University, Campus, Building E8.1, 66123, Saarbrücken, Germany. brigitta.loretz@helmholtz-hzi.de.ORCID 0000-0003-0057-5181
Claus-Michael LehrDepartment of Drug Delivery, Helmholtz-Institute for Pharmaceutical Research Saarland, Helmholtz-Centre for Infection Research Braunschweig, Saarland University, Campus, Building E8.1, 66123, Saarbrücken, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regioselective oxidation of water-soluble starch and conversion with alkyl diamines resulted in defined cationic starch derivatives. Those were assessed in their potential for polyplex formation, biocompatibility, and transfection efficacy. The new polymers have the advantage of being biodegradable, being not cytotoxic at rather high concentrations (LC

Indexed as

A549 Cellsalpha-AmylasesCell SurvivalDNAHEK293 CellsHumansLuciferasesPlasmidsStarchTransfectionalpha-AmylasesDNALuciferasesStarchGene therapyPlasmid DNAPolymeric nanoparticlesPolysaccharides

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.