Evidence map›Paper›PMID 27699238›Full record

ArticleJCI insight2016

Benjamin Steines, David D Dickey, Jamie Bergen, Katherine Jda Excoffon, John R Weinstein, Xiaopeng Li, Ziying Yan, Mahmoud H Abou Alaiwa, Viral S Shah, Drake C Bouzek and 9 more

Open access · goldAbstract read
In one paragraph

Article in JCI insight, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 90 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. DNA-PKcs Inhibition Improves Sequential Gene Insertion of the Full-LengthbioRxiv : the preprint server for biology · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
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  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 3 countries.

Benjamin SteinesDepartment of Internal Medicine.
David D DickeyDepartment of Internal Medicine.
Jamie BergenDepartments of Chemical and Biomolecular Engineering, Bioengineering, The Helen Wills Neuroscience Institute, Molecular and Cellular Biology, University of California, Berkeley, California, USA.
Katherine Jda ExcoffonDepartment of Biological Sciences, Wright State University, Dayton, Ohio, USA.
John R WeinsteinDepartments of Chemical and Biomolecular Engineering, Bioengineering, The Helen Wills Neuroscience Institute, Molecular and Cellular Biology, University of California, Berkeley, California, USA.
Xiaopeng LiDepartment of Internal Medicine.
Ziying YanAnatomy and Cell Biology.
Mahmoud H Abou AlaiwaDepartment of Internal Medicine.
Viral S ShahDepartment of Internal Medicine.
Drake C BouzekDepartment of Internal Medicine.
Linda S PowersDepartment of Internal Medicine.
Nicholas D GansemerDepartment of Internal Medicine.
Lynda S OstedgaardDepartment of Internal Medicine.
John F EngelhardtAnatomy and Cell Biology.
David A StoltzDepartment of Internal Medicine.
Michael J WelshDepartment of Internal Medicine.
Patrick L SinnPappajohn Biomedical Institute, Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, Iowa, USA.
David V SchafferDepartments of Chemical and Biomolecular Engineering, Bioengineering, The Helen Wills Neuroscience Institute, Molecular and Cellular Biology, University of California, Berkeley, California, USA.
Joseph ZabnerDepartment of Internal Medicine.
University of Iowa · USUniversity of California, San Francisco · USInstitute of Cell Biology and Neurobiology · ITInstitute of Molecular Biology and Biophysics · RUWright State University · US

Funding

Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Brandi Janssen · 1990 to 2026
$40.5M
Vector CoreP01HL051670 · NHLBI · UNIVERSITY OF IOWA · PI MCCRAY, PAUL B · 1993 to 2019
$36.5M
Respiratory virus infection in early cystic fibrosis lung diseaseP01HL091842 · NHLBI · UNIVERSITY OF IOWA · PI STOLTZ, DAVID A · 2008 to 2022
$34.2M
Vector Core-Core 2P30DK054759 · NIDDK · UNIVERSITY OF IOWA · PI Alejandro Antonio Pezzulo · 1998 to 2026
$30.5M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007337 · NIGMS · UNIVERSITY OF IOWA · PI GEYER, PAMELA K., LENTZ, STEVEN R · 1985 to 2020
$15.9M
NHLBI NIH HHS P01 HL051670NHLBI NIH HHS P01 HL091842NIDDK NIH HHS P30 DK054759NIEHS NIH HHS P30 ES005605NIGMS NIH HHS T32 GM007337
6 · The paper itself

Abstract

The physiological components that contribute to cystic fibrosis (CF) lung disease are steadily being elucidated. Gene therapy could potentially correct these defects.

Indexed as

Genetic VectorsAnimalsCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorDependovirusPhenotypeSwineCystic Fibrosis Transmembrane Conductance Regulator

Identifiers

PMID27699238
PMCPMC5033908
OpenAlexW2511571588

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.