Evidence map›Paper›PMID 27699207›Full record

ArticleeNeuro

Slow Cholinergic Modulation of Spike Probability in Ultra-Fast Time-Coding Sensory Neurons.

David Goyer, Stefanie Kurth, Charlène Gillet, Christian Keine, Rudolf Rübsamen, Thomas Kuenzel

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. A Developmental Switch in Cholinergic Mechanisms of Modulation in the Medial Nucleus of the Trapezoid Body.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  6. Cholinergic modulation in the vertebrate auditory pathway.Frontiers in cellular neuroscience · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Endogenous Cholinergic Signaling Modulates Sound-Evoked Responses of the Medial Nucleus of the Trapezoid Body.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  11. αFrontiers in neural circuits · 2021
    Article
  12. Article
  13. Review
  14. Article
  15. Article
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  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

David GoyerInstitute for Biology II, Department of Zoology/Animal Physiology, RWTH Aachen University , D-52074 Aachen, Germany.
Stefanie KurthInstitute for Biology II, Department of Zoology/Animal Physiology, RWTH Aachen University , D-52074 Aachen, Germany.
Charlène GilletInstitute for Biology II, Department of Zoology/Animal Physiology, RWTH Aachen University , D-52074 Aachen, Germany.ORCID 0000-0002-4448-1200
Christian KeineInstitute of Biology, Faculty of Biosciences, Pharmacy and Psychology, University of Leipzig , D-04103 Leipzig, Germany.ORCID 0000-0002-8953-2593
Rudolf RübsamenInstitute of Biology, Faculty of Biosciences, Pharmacy and Psychology, University of Leipzig , D-04103 Leipzig, Germany.
Thomas KuenzelInstitute for Biology II, Department of Zoology/Animal Physiology, RWTH Aachen University , D-52074 Aachen, Germany.ORCID 0000-0003-0993-8524
RWTH Aachen University · DELeipzig University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sensory processing in the lower auditory pathway is generally considered to be rigid and thus less subject to modulation than central processing. However, in addition to the powerful bottom-up excitation by auditory nerve fibers, the ventral cochlear nucleus also receives efferent cholinergic innervation from both auditory and nonauditory top-down sources. We thus tested the influence of cholinergic modulation on highly precise time-coding neurons in the cochlear nucleus of the Mongolian gerbil. By combining electrophysiological recordings with pharmacological application

Indexed as

AcetylcholineAction PotentialsAnimalsCarbacholCholinergic AgentsComputer SimulationGerbillinaeModels, NeurologicalReceptors, MuscarinicReceptors, NicotinicSensory Receptor CellsSynapsesTissue Culture TechniquesAcetylcholineCarbacholCholinergic AgentsReceptors, MuscarinicReceptors, Nicotinicacetylcholineanteroventral cochlear nucleusgerbilmeriones unguiculatusolivocochlear bundlespherical bushy cell

Identifiers

PMID27699207
PMCPMC5035776
OpenAlexW2520125286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.