Evidence map›Paper›PMID 27699181›Full record

ReviewJournal of immunology research2016

Characteristics of HLA-E Restricted T-Cell Responses and Their Role in Infectious Diseases.

Simone A Joosten, Lucy C Sullivan, Tom H M Ottenhoff

Open access · goldAbstract readReview
In one paragraph

Review in Journal of immunology research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 94 citations in OpenAlex.

  1. Donor HLA-E Status Associates with Disease-Free Survival and Transplant-Related Mortality after Non In Vivo T Cell-Depleted HSCT for Acute Leukemia.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2019
    Trial
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  12. Instability of the HLA-E peptidome of HIV presents a major barrier to therapeutic targeting.Molecular therapy : the journal of the American Society of Gene Therapy · 2024
    Article
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  14. Review
  15. Human CD8Immune network · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Simone A JoostenDepartment of Infectious Diseases, Leiden University Medical Center, 2333 ZA Leiden, Netherlands.ORCID 0000-0002-9878-0863
Lucy C SullivanDepartment of Microbiology and Immunology, The University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3010, Australia.ORCID 0000-0003-2907-4989
Tom H M OttenhoffDepartment of Infectious Diseases, Leiden University Medical Center, 2333 ZA Leiden, Netherlands.
Leiden University Medical Center · NLThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human HLA-E can, in addition to self-antigens, also present pathogen-derived sequences, which elicit specific T-cell responses. T-cells recognize their antigen presented by HLA-E highly specifically and have unique functional and phenotypical properties. Pathogen specific HLA-E restricted CD8

Indexed as

Adaptive ImmunityAnimalsAntigensCommunicable DiseasesEpitopes, T-LymphocyteHistocompatibility Antigens Class IHLA-E AntigensHumansImmunity, InnateProtein BindingReceptors, Antigen, T-CellT-LymphocytesAntigensEpitopes, T-LymphocyteHistocompatibility Antigens Class IHLA-E AntigensReceptors, Antigen, T-Cell

Identifiers

PMID27699181
PMCPMC5028793
OpenAlexW2513660241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.