Evidence map›Paper›PMID 27699167›Full record

ReviewBioMed research international2016

Obstructive Sleep Apnea in Women: Specific Issues and Interventions.

Alison Wimms, Holger Woehrle, Sahisha Ketheeswaran, Dinesh Ramanan, Jeffery Armitstead

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05210998 (Investigation of the Effects of Respiratory Muscle Training Combined With Aerobic Exercise in Persons With Obstructive Sleep Apnea Syndrome), which is not on this map. Cited by 103 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed, 2 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05210998 nacompletednot on this mapstarted 2022, after this paper: background citation

Investigation of the Effects of Respiratory Muscle Training Combined With Aerobic Exercise in Persons With Obstructive Sleep Apnea Syndrome

TypeinterventionalSponsorIstanbul University - CerrahpasaRan2022 to 2023Enrolled36ConditionsObstructive Sleep Apnea SyndromeArmsGradual Aerobic exercise training AND Respiratory muscle training, Gradual Aerobic exercise training
3 · Its place in the literature

Who cites it

103 citing papers in PubMed, 2 syntheses or guidelines pooled it, 170 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Association of tirzepatide with changes in OSA-related measures based on baseline characteristics - post hoc analyses of SURMOUNT-OSA.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Trial
  4. Osa in women: When does cpap increase blood pressure?Sleep & breathing = Schlaf & Atmung · 2025
    Trial
  5. Trial
  6. Trial
  7. Trial
  8. Review
  9. The effect of gender on clinical characteristics and diagnostic process of obstructive sleep apnea syndrome.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  10. Review
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  20. Article

43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Alison WimmsResMed Science Centre, Fraunhoferstraße 16, 82152 Planegg, Germany; University of Sydney, Fisher Road, Sydney, NSW, Australia.ORCID 0000-0003-4735-8328
Holger WoehrleResMed Science Centre, Fraunhoferstraße 16, 82152 Planegg, Germany; Sleep and Ventilation Center Blaubeuren, Lung Center Ulm, Ulm, Germany.
Sahisha KetheeswaranResMed Science Centre, Fraunhoferstraße 16, 82152 Planegg, Germany.
Dinesh RamananResMed Science Centre, Fraunhoferstraße 16, 82152 Planegg, Germany.
Jeffery ArmitsteadResMed Science Centre, Fraunhoferstraße 16, 82152 Planegg, Germany.
ResMed (Germany) · DEThe University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obstructive sleep apnea (OSA) has traditionally been seen as a male disease. However, the importance of OSA in women is increasingly being recognized, along with a number of significant gender-related differences in the symptoms, diagnosis, consequences, and treatment of OSA. Women tend to have less severe OSA than males, with a lower apnea-hypopnea index (AHI) and shorter apneas and hypopneas. Episodes of upper airway resistance that do not meet the criteria for apneas are more common in women. Prevalence rates are lower in women, and proportionally fewer women receive a correct diagnosis. Research has also documented sex differences in the upper airway, fat distribution, and respiratory stability in OSA. Hormones are implicated in some gender-related variations, with differences between men and women in the prevalence of OSA decreasing as age increases. The limited data available suggest that although the prevalence and severity of OSA may be lower in women than in men, the consequences of the disease are at least the same, if not worse for comparable degrees of severity. Few studies have investigated gender differences in the effects of OSA treatment. However, given the differences in physiology and presentation, it is possible that personalized therapy may provide more optimal care.

Indexed as

FemaleHumansPrevalenceRespirationSex CharacteristicsSleep Apnea, Obstructive

Identifiers

PMID27699167
PMCPMC5028797
OpenAlexW2183727450

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.