Evidence map›Paper›PMID 27699107›Full record

ArticleBiomedical optics express2016

Dual-modality endomicroscopy with co-registered fluorescence and phase contrast.

C Ba, M Palmiere, J Ritt, J Mertz

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

C BaBiomedical Engineering Department, Boston University, 44 Cummington Mall, Boston, MA 02215, USA.
M PalmiereBiomedical Engineering Department, Boston University, 44 Cummington Mall, Boston, MA 02215, USA.
J RittBiomedical Engineering Department, Boston University, 44 Cummington Mall, Boston, MA 02215, USA.
J MertzBiomedical Engineering Department, Boston University, 44 Cummington Mall, Boston, MA 02215, USA.

Funding

High resolution phase contrast endoscopyR01CA182939 · NCI · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI MERTZ, JEROME · 2014 to 2017
$1.4M
Ultra-miniaturized single fiber probe for functional brain imaging in freely moving animalsR21EY026310 · NEI · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI MERTZ, JEROME · 2015 to 2016
$486k
Multi-region, extended-depth imaging of neural activity via a novel needle microendoscopeR21EB020851 · NIBIB · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI MERTZ, JEROME, RITT, JASON T · 2015 to 2016
$450k
NCI NIH HHS R01 CA182939NEI NIH HHS R21 EY026310NIBIB NIH HHS R21 EB020851
6 · The paper itself

Abstract

We describe a dual-modality laser scanning endomicroscope that provides simultaneous fluorescence contrast based on confocal laser endomicroscopy (CLE) and phase-gradient contrast based on scanning oblique back-scattering microscopy (sOBM). The probe consists of a 2.6mm-diameter micro-objective attached to a 30,000-core flexible fiber bundle. The dual contrasts are inherently co-registered, providing complementary information on labeled and un-labeled sample structure. Proof of principle demonstrations are presented with ex-vivo mouse colon tissue.

Indexed as

(120.5050) Phase measurement(170.1790) Confocal microscopy(170.2150) Endoscopic imaging(180.5810) Scanning microscopy

Identifiers

PMID27699107
PMCPMC5030019

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.