Evidence map›Paper›PMID 27699003›Full record

ArticleAnnals of medicine and surgery (2012)2016

Using electronic health record collected clinical variables to predict medical intensive care unit mortality.

Jacob Calvert, Qingqing Mao, Jana L Hoffman, Melissa Jay, Thomas Desautels, Hamid Mohamadlou, Uli Chettipally, Ritankar Das

6 registry-linked trialsAbstract read
In one paragraph

Article in Annals of medicine and surgery (2012), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 6 registered trials, which are not on this map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03212534 nawithdrawnnot on this mapstarted 2017, after this paper: background citation

A Randomized Clinical Trial of a Mortality Prediction Algorithm

TypeinterventionalSponsorDascenaRan2017 to 2017Enrolled0ConditionsDecompensation, Heart, Decompensation, Heart, Congestive, DeathArmsPatient mortality prediction
NCT03644940 phase2withdrawnnot on this mapstarted 2020, after this paper: background citation

Subpopulation-Specific Sepsis Identification Using Machine Learning

TypeinterventionalSponsorDascenaRan2020 to 2021Enrolled0ConditionsSepsis, Severe Sepsis, Septic ShockArmsCustomSight
NCT03734484 phase2withdrawnnot on this mapstarted 2022, after this paper: background citation

Gram Type Infection-Specific Sepsis Identification Using Machine Learning

TypeinterventionalSponsorDascenaRan2022 to 2023Enrolled0ConditionsSepsis, Severe Sepsis, Septic ShockArmsInSight
NCT03752489 phase2unknown statusnot on this mapstarted 2022, after this paper: background citation

Unsupervised Machine Learning for Clustering of Septic Patients to Determine Optimal Treatment

TypeinterventionalSponsorDascenaRan2022 to 2024Enrolled51,645ConditionsSepsis, Severe Sepsis, Septic ShockArmsTreatment-specific InSight, InSight
NCT03882476 phase2withdrawnnot on this mapstarted 2020, after this paper: background citation

Randomized Controlled Trial of a Machine Learning Algorithm for Early Sepsis Detection

TypeinterventionalSponsorDascenaRan2020 to 2021Enrolled0ConditionsSepsis, Severe Sepsis, Septic ShockArmsInSight
NCT04005001 phase2unknown statusnot on this mapstarted 2021, after this paper: background citation

Using Clinical Treatment Data in a Machine Learning Approach for Sepsis Detection

TypeinterventionalSponsorDascenaRan2021 to 2022Enrolled37,986ConditionsSepsis, Severe Sepsis, Septic ShockArmsHindSight, InSight
3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
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  11. Observational
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  18. Early Hospital Mortality Prediction using Vital Signals.Smart health (Amsterdam, Netherlands) · 2018
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jacob CalvertDascena Inc., Hayward, CA, USA.
Qingqing MaoDascena Inc., Hayward, CA, USA.
Jana L HoffmanDascena Inc., Hayward, CA, USA.
Melissa JayDascena Inc., Hayward, CA, USA.
Thomas DesautelsDascena Inc., Hayward, CA, USA.
Hamid MohamadlouDascena Inc., Hayward, CA, USA.
Uli ChettipallyKaiser Permanente South San Francisco Medical Center, South San Francisco, CA, USA; Department of Emergency Medicine, University of California San Francisco, San Francisco, CA, USA.
Ritankar DasDascena Inc., Hayward, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClinical decision support systems are used to help predict patient stability and mortality in the Intensive Care Unit (ICU). Accurate patient information can assist clinicians with patient management and in allocating finite resources. However, systems currently in common use have limited predictive value in the clinical setting. The increasing availability of Electronic Health Records (EHR) provides an opportunity to use medical information for more accurate patient stability and mortality prediction in the ICU.

objectiveDevelop and evaluate an algorithm which more accurately predicts patient mortality in the ICU, using the correlations between widely available clinical variables from the EHR.

methodsWe have developed an algorithm,

results

conclusionsThrough the multidimensional analysis of the correlations between eight common clinical variables,

Indexed as

Clinical decision support systemsElectronic health recordsMedical informaticsMortality prediction

Identifiers

PMID27699003
PMCPMC5037117

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.