Evidence map›Paper›PMID 27698916›Full record

ArticleJournal of Cancer2016

Diet- and Genetically-induced Obesity Produces Alterations in the Microbiome, Inflammation and

Wei Liu, Jimmy W Crott, Lin Lyu, Anna C Pfalzer, Jinchao Li, Sang-Woon Choi, Yingke Yang, Joel B Mason, Zhenhua Liu

Abstract read
In one paragraph

Article in Journal of Cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Systematic review: The gut microbiota as a link between colorectal cancer and obesity.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Associations between the gut microbiota and host responses to high altitude.American journal of physiology. Gastrointestinal and liver physiology · 2018
    Trial
  5. Article
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  11. Murine Models of Obesity-Related Cancer Risk.Cancer prevention research (Philadelphia, Pa.) · 2025
    Review
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  13. Article
  14. Article
  15. Article
  16. Experimental Inoculation ofInternational journal of molecular sciences · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wei LiuNutrition and Cancer Prevention Laboratory, School of Public Health and Health Sciences, University of Massachusetts, Amherst, USA.; Institute of Food Science and Technology, Shandong Academy of Agricultural Sciences, Jinan, China.
Jimmy W CrottJean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, USA.
Lin LyuNutrition and Cancer Prevention Laboratory, School of Public Health and Health Sciences, University of Massachusetts, Amherst, USA.
Anna C PfalzerJean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, USA.
Jinchao LiNutrition and Cancer Prevention Laboratory, School of Public Health and Health Sciences, University of Massachusetts, Amherst, USA.
Sang-Woon ChoiNutrition and Cancer Prevention Laboratory, School of Public Health and Health Sciences, University of Massachusetts, Amherst, USA.; CHA Cancer Research Center, CHA University, Seoul, Korea.
Yingke YangDepartment of Molecular Medicine, Hunan University, Changsha, China.
Joel B MasonJean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, USA.; Tufts Medical Center Cancer Center, Tufts University, Boston, USA.
Zhenhua LiuNutrition and Cancer Prevention Laboratory, School of Public Health and Health Sciences, University of Massachusetts, Amherst, USA.; Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity is an established risk factor for colorectal cancer (CRC). Our previous study indicated that obesity increases activity of the pro-tumorigenic

Indexed as

InflammationIntestinal cancer.MicrobiomeObesityWnt pathway

Identifiers

PMID27698916
PMCPMC5039360

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.