Evidence map›Paper›PMID 27698869›Full record

ArticleOncology letters2016

RNA-seq analysis identifies key long non-coding RNAs connected to the pathogenesis of alcohol-associated head and neck squamous cell carcinoma.

Vicky Yu, Pranav Singh, Elham Rahimy, Hao Zheng, Selena Z Kuo, Elizabeth Kim, Jessica Wang-Rodriguez, Weg M Ongkeko

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. The repertoire of mutational signatures in tobacco- and non-tobacco-induced oral cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Epimutational effects of electronic cigarettes.Environmental science and pollution research international · 2021
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Vicky YuDepartment of Surgery, Division of Otolaryngology-Head and Neck Surgery, University of California San Diego, San Diego, CA 92161, USA.
Pranav SinghDepartment of Surgery, Division of Otolaryngology-Head and Neck Surgery, University of California San Diego, San Diego, CA 92161, USA.
Elham RahimyDepartment of Surgery, Division of Otolaryngology-Head and Neck Surgery, University of California San Diego, San Diego, CA 92161, USA.
Hao ZhengDepartment of Surgery, Division of Otolaryngology-Head and Neck Surgery, University of California San Diego, San Diego, CA 92161, USA.
Selena Z KuoDepartment of Surgery, Division of Otolaryngology-Head and Neck Surgery, University of California San Diego, San Diego, CA 92161, USA.
Elizabeth KimDepartment of Surgery, Division of Otolaryngology-Head and Neck Surgery, University of California San Diego, San Diego, CA 92161, USA.
Jessica Wang-RodriguezDepartment of Pathology, Veterans Administration Medical Center, University of California San Diego, San Diego, CA 92161, USA.
Weg M OngkekoDepartment of Surgery, Division of Otolaryngology-Head and Neck Surgery, University of California San Diego, San Diego, CA 92161, USA.
University of California, San Diego · USUniversity of California San Diego Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcohol consumption has been implicated in the pathogenesis of head and neck squamous cell carcinoma (HNSCC), although its mechanism is poorly understood. Recent advances in the identification and understanding of long non-coding RNAs (lncRNAs) have indicated that these molecules have a profound effect on numerous biological processes, including tumorigenesis and oncogenesis. The present authors hypothesize that alcohol-mediated dysregulation of lncRNAs is a key event in HNSCC pathogenesis. An

Indexed as

acetaldehydealcoholepigeneticshead and neck squamous cell carcinomalong non-coding RNAsRNA-seq

Identifiers

PMID27698869
PMCPMC5038566
OpenAlexW2514216267

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.