Evidence map›Paper›PMID 27698780›Full record

ArticleExperimental and therapeutic medicine2016

miR-448 downregulates MPPED2 to promote cancer proliferation and inhibit apoptosis in oral squamous cell carcinoma.

Linhan Shen, Liu Liu, Liangyu Ge, Long Xie, Siyu Liu, Lei Sang, Tiantian Zhan, Hongwei Li

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. Trial
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  9. TheCancers · 2019
    Article
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  11. Frontiers in genetics · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Linhan ShenJiangsu Key Laboratory of Oral Diseases, Institute of Stomatology, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Liu LiuJiangsu Key Laboratory of Oral Diseases, Institute of Stomatology, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Liangyu GeJiangsu Key Laboratory of Oral Diseases, Institute of Stomatology, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Long XieDepartment of Oral and Maxillofacial Surgery, Hospital of Stomatology, Wuhan University, Wuhan, Hubei 430079, P.R. China.
Siyu LiuJiangsu Key Laboratory of Oral Diseases, Institute of Stomatology, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Lei SangDepartment of Oral and Maxillofacial Surgery, Suzhou Huaxia Stomatological Hospital, Suzhou, Jiangsu 215002, P.R. China.
Tiantian ZhanJiangsu Key Laboratory of Oral Diseases, Institute of Stomatology, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Hongwei LiJiangsu Key Laboratory of Oral Diseases, Institute of Stomatology, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China; Jiangsu Key Laboratory of Oral Diseases, Department of Oral and Maxillofacial Surgery, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, Jiangsu 210029 P.R. China.
Nanjing Medical University · CNWuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of oral squamous cell carcinoma (OSCC) is continuously increasing while its survival rate has not notably improved. There is a pressing need for improved understanding of the genetic regulation of OSCC tumorigenesis and progression. In this study, the function of miR-448 in the regulation of OSCC growth and its putative target were thoroughly analyzed

Indexed as

miR-448MPPED2oral squamous cell carcinoma

Identifiers

PMID27698780
PMCPMC5038171
OpenAlexW2514304279

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.