Evidence map›Paper›PMID 27698732›Full record

ArticleExperimental and therapeutic medicine2016

Recombinant expression and biological characterization of the antimicrobial peptide fowlicidin-2 in

Li-Wei Xing, Shi-Xun Tian, Wei Gao, Na Yang, Pei Qu, Di Liu, Jian Jiao, Jue Wang, Xing-Jun Feng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental and therapeutic medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Porcine β-Defensin 2 Expressed inAnimals : an open access journal from MDPI · 2025
    Article
  6. Article
  7. Review
  8. Review
  9. A eukaryotic expression strategy for producing the novel antimicrobial peptide PRW4.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020
    Article
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Li-Wei XingDepartment of Animal Nutrition and Feed Science, College of Animal Science and Technology, Northeast Agricultural University, Harbin, Heilongjiang 150030, P.R. China.
Shi-Xun TianDepartment of Animal Nutrition and Feed Science, College of Animal Science and Technology, Northeast Agricultural University, Harbin, Heilongjiang 150030, P.R. China.
Wei GaoDepartment of Animal Nutrition and Feed Science, College of Animal Science and Technology, Northeast Agricultural University, Harbin, Heilongjiang 150030, P.R. China.
Na YangDepartment of Animal Nutrition and Feed Science, College of Animal Science and Technology, Northeast Agricultural University, Harbin, Heilongjiang 150030, P.R. China.
Pei QuDepartment of Animal Nutrition and Feed Science, College of Animal Science and Technology, Northeast Agricultural University, Harbin, Heilongjiang 150030, P.R. China.
Di LiuDepartment of Animal Nutrition and Feed Science, College of Animal Science and Technology, Northeast Agricultural University, Harbin, Heilongjiang 150030, P.R. China.
Jian JiaoDepartment of Animal Nutrition and Feed Science, College of Animal Science and Technology, Northeast Agricultural University, Harbin, Heilongjiang 150030, P.R. China.
Jue WangDepartment of Animal Nutrition and Feed Science, College of Animal Science and Technology, Northeast Agricultural University, Harbin, Heilongjiang 150030, P.R. China.
Xing-Jun FengDepartment of Animal Nutrition and Feed Science, College of Animal Science and Technology, Northeast Agricultural University, Harbin, Heilongjiang 150030, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fowlicidins are a group of cathelicidin antimicrobial peptides that were initially identified in chickens. Fowlicidin-2, which is composed of 31 amino acids, is widely expressed in the majority of tissues in chickens and has an important role in innate immunity. In the present study, a recombinant expression system for fowlicidin-2 was successfully constructed using

Indexed as

antibacterial activityanticancer activityantimicrobial peptidesfowlicidin-2Pichia pastorisrecombinant expression

Identifiers

PMID27698732
PMCPMC5038210

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.