Evidence map›Paper›PMID 27698676›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2016

Hyeonggaeyeongyo-Tang for Treatment of Allergic and Nonallergic Rhinitis: A Prospective, Nonrandomized, Pre-Post Study.

Min-Hee Kim, Jaewoong Son, Hae Jeong Nam, Seong-Gyu Ko, Inhwa Choi

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02477293 (The Efficacy and Safety of Hyeonggaeyeongyo-tang for Chronic Rhinitis According to Pattern Identification in Korean Medicine), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02477293 phase4completednot on this map

The Efficacy and Safety of Hyeonggaeyeongyo-tang for Chronic Rhinitis According to Pattern Identification in Korean Medicine

TypeinterventionalSponsorKyung Hee University Hospital at GangdongRan2015 to 2016Enrolled40ConditionsRespiratory Tract Diseases, Nose Diseases, RhinitisArmsHyeonggaeyeongyo-tang
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Min-Hee KimDepartment of Clinical Korean Medicine, Graduate School, Kyung Hee University, Seoul, Republic of Korea; Department of Otorhinolaryngology of Korean Medicine, Kyung Hee University Hospital at Gangdong, Seoul, Republic of Korea.ORCID 0000-0002-6593-2410
Jaewoong SonDepartment of Clinical Korean Medicine, Graduate School, Kyung Hee University, Seoul, Republic of Korea; Department of Otorhinolaryngology of Korean Medicine, Kyung Hee University Hospital at Gangdong, Seoul, Republic of Korea.ORCID 0000-0002-0133-9458
Hae Jeong NamDepartment of Ophthalmology & Otorhinolaryngology, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.ORCID 0000-0002-9974-0863
Seong-Gyu KoDepartment of Preventive Medicine, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.ORCID 0000-0002-2345-430X
Inhwa ChoiDepartment of Otorhinolaryngology of Korean Medicine, Kyung Hee University Hospital at Gangdong, Seoul, Republic of Korea; Department of Ophthalmology & Otorhinolaryngology, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.ORCID 0000-0001-7416-2772
Kyung Hee University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyeonggaeyeongyo-tang (HYT) is an ancient formula of oriental medicine traditionally used to treat rhinitis; however, clinical evidence has not yet been established. The aim of this study was to investigate the short-term and long-term efficacy and safety of HYT for chronic rhinitis. Adult subjects with chronic rhinitis symptoms were recruited. The subjects received HYT for 4 weeks and had follow-up period of 8 weeks. Any medicines used to treat nasal symptoms were not permitted during the study. The skin prick test was performed to distinguish the subjects with allergic rhinitis from those with nonallergic rhinitis. After treatment, the total nasal symptoms score and the Rhinoconjunctivitis Quality of Life Questionnaire score significantly improved in the whole subject group, in the allergic rhinitis group, and in the nonallergic rhinitis group, with no adverse events. This improvement lasted during a follow-up period of 8 weeks. Total IgE and eosinophil levels showed no significant difference after treatment in the allergic rhinitis group. HYT improved nasal symptoms and quality of life in patients with allergic rhinitis and nonallergic rhinitis. This is the first clinical study to evaluate the use of HYT to treat patients with rhinitis. This trial has been registered with the ClinicalTrials.gov Identifier NCT02477293.

Identifiers

PMID27698676
PMCPMC5028861
OpenAlexW2519849803

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.