Trial reportClinical interventions in aging2016
Effects of combined physical and cognitive training on fitness and neuropsychological outcomes in healthy older adults.
Trial report in Clinical interventions in aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 62 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Virtual Reality Motor-cognitive Training for Older People With Cognitive Frailty: A Pilot Trial
Virtual Reality Motor-cognitive Training for Older People With Cognitive Frailty: The Implementation of the Prototype
Who cites it
62 citing papers in PubMed, 10 syntheses or guidelines pooled it, 122 citations in OpenAlex.
- Effectiveness of dual-task exercise in improving balance and preventing falls among older adults: systematic review with meta-analysis and meta-regression.European geriatric medicine · 2025Pooled it
- Behaviour Change Techniques in Computerized Cognitive Training for Cognitively Healthy Older Adults: A Systematic Review.Neuropsychology review · 2023Pooled it
- Impact of Motor-Cognitive Interventions on Selected Gait and Balance Outcomes in Older Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Frontiers in psychology · 2022Pooled it
- The Effects of Combined Cognitive-Physical Interventions on Cognitive Functioning in Healthy Older Adults: A Systematic Review and Multilevel Meta-Analysis.Frontiers in human neuroscience · 2022Pooled it
- Computerised cognitive training for 12 or more weeks for maintaining cognitive function in cognitively healthy people in late life.The Cochrane database of systematic reviews · 2020Pooled it
- The effects of same-session combined exercise training on cardiorespiratory and functional fitness in older adults: a systematic review and meta-analysis.Aging clinical and experimental research · 2019Pooled it
- Computerised cognitive training for preventing dementia in people with mild cognitive impairment.The Cochrane database of systematic reviews · 2019Pooled it
- Computerised cognitive training for maintaining cognitive function in cognitively healthy people in late life.The Cochrane database of systematic reviews · 2019Pooled it
- Computerised cognitive training for maintaining cognitive function in cognitively healthy people in midlife.The Cochrane database of systematic reviews · 2019Pooled it
- Physical activity to improve cognition in older adults: can physical activity programs enriched with cognitive challenges enhance the effects? A systematic review and meta-analysis.The international journal of behavioral nutrition and physical activity · 2018Pooled it
- Optimizing Cognitive and Physical Gains in Older Adults: Benefits of a Psychomotor Intervention Program Based on Functional Level.Medicina (Kaunas, Lithuania) · 2025Trial
- Trial
- Benefits of Two 24-Week Interactive Cognitive-Motor Programs on Body Composition, Lower-Body Strength, and Processing Speed in Community Dwellings at Risk of Falling: A Randomized Controlled Trial.International journal of environmental research and public health · 2022Trial
- The Effects of the Combination of High-Intensity Interval Training with 3D-Multiple Object Tracking Task on Perceptual-Cognitive Performance: A Randomized Controlled Intervention Trial.International journal of environmental research and public health · 2021Trial
- Investigating dose-response effects of multimodal exercise programs on health-related quality of life in older adults.Clinical interventions in aging · 2019Trial
- The interactive Physical and Cognitive Exercise System (iPACES™): effects of a 3-month in-home pilot clinical trial for mild cognitive impairment and caregivers.Clinical interventions in aging · 2018Trial
- Associations Between Sports-Based After-School Activities, Cognitive Ability, Physical Health, Problematic Internet Use, Psychosocial Health, and Health-Related Behaviors Among Indonesian Adolescents.Journal of the Korean Academy of Child and Adolescent Psychiatry · 2026Article
- Effects of different training characteristics in combined resistance and cognitive training on motor and cognitive performance in older adults: A systematic review.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026Review
- Impact of two different periodized aerobic training on acute cerebrovascular response and cognitive performance in coronary heart disease patients.Physiological reports · 2025Article
- Physical activity and neuroplasticity in neurodegenerative disorders: a comprehensive review of exercise interventions, cognitive training, and AI applications.Frontiers in neuroscience · 2025Review
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePhysical exercise and cognitive training have been shown to enhance cognition among older adults. However, few studies have looked at the potential synergetic effects of combining physical and cognitive training in a single study. Prior trials on combined training have led to interesting yet equivocal results. The aim of this study was to examine the effects of combined physical and cognitive interventions on physical fitness and neuropsychological performance in healthy older adults.
methodsSeventy-six participants were randomly assigned to one of four training combinations using a 2×2 factorial design. The physical intervention was a mixed aerobic and resistance training program, and the cognitive intervention was a dual-task (DT) training program. Stretching and toning exercises and computer lessons were used as active control conditions. Physical and cognitive measures were collected pre- and postintervention.
resultsAll groups showed equivalent improvements in measures of functional mobility. The aerobic-strength condition led to larger effect size in lower body strength, independently of cognitive training. All groups showed improved speed of processing and inhibition abilities, but only participants who took part in the DT training, independently of physical training, showed increased task-switching abilities. The level of functional mobility after intervention was significantly associated with task-switching abilities.
conclusionCombined training did not yield synergetic effects. However, DT training did lead to transfer effects on executive performance in neuropsychological tests. Both aerobic-resistance training and stretching-toning exercises can improve functional mobility in older adults.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.