ReviewThe Ulster medical journal2016
Pruritus: an overview. What drives people to scratch an itch?
Review in The Ulster medical journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 37 citations in OpenAlex.
- Updates in the Treatment of Pain and Pruritus in Epidermolysis Bullosa.Pediatric dermatology · 2026Review
- Anti-Inflammation and Anti-Hypersensitivity Effects ofPreventive nutrition and food science · 2025Article
- Assessing the impact of tungiasis on children's quality of life in Kenya.PLoS neglected tropical diseases · 2025Article
- Involvement of Pruritus, Gut Dysbiosis and Histamine-Producing Bacteria in Paraneoplastic Syndromes.Biomedicines · 2025Article
- Soothing the Itch: The Role of Medicinal Plants in Alleviating Pruritus in Palliative Care.Plants (Basel, Switzerland) · 2024Review
- Anti-inflammatory Capacity of a Medicinal herb extract,Heliyon · 2024Article
- Psychodermatology of Chronic Pruritus: An Overview of the Link Between Itch and Distress.Dermatology and therapy · 2024Review
- Apigenin: A Therapeutic Agent for Treatment of Skin Inflammatory Diseases and Cancer.International journal of molecular sciences · 2023Review
- Study of the Involvement of the P2Y12 Receptor in Chronic Itching in Type 2 Diabetes Mellitus.Molecular neurobiology · 2022Article
- Neuroinflammation Involved in Diabetes-Related Pain and Itch.Frontiers in pharmacology · 2022Review
- Multilineage-differentiating stress-enduring cells alleviate atopic dermatitis-associated behaviors in mice.Stem cell research & therapy · 2021Article
- Responses of neurons in the primary somatosensory cortex to itch- and pain-producing stimuli in rats.Journal of neurophysiology · 2020Article
- Have We Just Scratched the Surface? A Narrative Review of Uremic Pruritus in 2020.Canadian journal of kidney health and disease · 2020Review
- Water-Soluble Extract fromNutrients · 2019Article
- Effect of Resveratrol-Enriched Rice on Skin Inflammation and Pruritus in the NC/Nga Mouse Model of Atopic Dermatitis.International journal of molecular sciences · 2019Article
- Responses of thalamic neurons to itch- and pain-producing stimuli in rats.Journal of neurophysiology · 2018Article
- Pruritus: Progress toward Pathogenesis and Treatment.BioMed research international · 2018Review
- Is Itch Intensity in Atopic Dermatitis Associated with Skin Colonization byIndian journal of dermatologyArticle
- Chronic pruritus: a narrative review.Anais brasileiros de dermatologiaReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pruritus is a common complaint associated with many conditions. It negatively impacts sleep, quality of life, and mortality. Itch is transmitted along both histaminergic and non-histaminergic pathways with a complex interplay between keratinocytes, immune cells and cutaneous neurons. Individuals who present with pruritus should undergo a thorough assessment, especially those over 65 years old, to exclude underlying malignancy. Treatment no longer consists of antihistamines alone. Physicians now have an array of therapies in their armamentarium, to help alleviate this distressing symptom.
Indexed as
Identifiers
27698518PMC5031103W2545291810What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.