Evidence map›Paper›PMID 27698514›Full record

ArticleTetrahedron2016

Synthesis of Psoralidin derivatives and their anticancer activity: First synthesis of Lespeflorin I

Pallab Pahari, Ujwal Pratim Saikia, Trinath Prasad Das, Chendil Damodaran, Jurgen Rohr

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tetrahedron, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pallab PahariChemical Science and Technology Division, CSIR - North East Institute of Science & Technology, Jorhat-785006, Assam, India; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 S. Limestone St., Lexington, Kentucky-40536, United States.
Ujwal Pratim SaikiaChemical Science and Technology Division, CSIR - North East Institute of Science & Technology, Jorhat-785006, Assam, India.
Trinath Prasad DasDepartment of Urology, University of Louisville, Louisville, KY 40292, United States.
Chendil DamodaranDepartment of Urology, University of Louisville, Louisville, KY 40292, United States.
Jurgen RohrDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 S. Limestone St., Lexington, Kentucky-40536, United States.

Funding

NOVEL AUREOLIC ACID TYPE ANTITUMOR AGENTSR01CA091901 · NCI · UNIVERSITY OF KENTUCKY · PI ROHR, JURGEN T · 2001 to 2017
$3.6M
Exploring Post-Type II PKS Frame ModificationsR01GM105977 · NIGMS · UNIVERSITY OF KENTUCKY · PI ROHR, JURGEN T · 2014 to 2017
$1.1M
NCI NIH HHS R01 CA091901NIGMS NIH HHS R01 GM105977United States NCIUnited States NIGMS
6 · The paper itself

Abstract

Synthetic scheme for the preparation of a number of different derivatives of anticancer natural product Psoralidin is described. A convergent synthetic approach is followed using simple starting materials like substituted phenyl acetic esters and benzoic acids. The developed synthetic route leads us to complete the first synthesis of an analogous natural product Lespeflorin I

Identifiers

PMID27698514
PMCPMC5044874

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.