Evidence map›Paper›PMID 27698445›Full record

ArticleLeukemia2017

CARMA1 is a novel regulator of T-ALL disease and leukemic cell migration to the CNS.

S R Oruganti, D J Torres, S Krebsbach, F Asperti-Boursin, J Winters, K Matlawska-Wasowska, S S Winter, C Halsey, J L Cannon

Open access · hybridAbstract readLetter
In one paragraph

Article in Leukemia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.9field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
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  8. Review
  9. Application of Metabolomics in Childhood Leukemia Diagnostics.Archivum immunologiae et therapiae experimentalis · 2022
    Review
  10. Management of CNS Disease in Pediatric Acute Lymphoblastic Leukemia.Current hematologic malignancy reports · 2022
    Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

S R OrugantiDepartment of Molecular Genetics and Microbiology, University of New Mexico Health Sciences Center, Albuquerque, Mexico.
D J TorresDepartment of Mathematics and Physical Science, Northern New Mexico College, Espanola, Mexico.
S KrebsbachDepartment of Molecular Genetics and Microbiology, University of New Mexico Health Sciences Center, Albuquerque, Mexico.
F Asperti-BoursinDepartment of Molecular Genetics and Microbiology, University of New Mexico Health Sciences Center, Albuquerque, Mexico.
J WintersDepartment of Molecular Genetics and Microbiology, University of New Mexico Health Sciences Center, Albuquerque, Mexico.
K Matlawska-WasowskaDepartment of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, Mexico.
S S WinterDepartment of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, Mexico.
C HalseyWolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow and Royal Hospital for Children, Glasgow, Scotland.
J L CannonDepartment of Molecular Genetics and Microbiology, University of New Mexico Health Sciences Center, Albuquerque, Mexico.
University of New Mexico · USNorthern New Mexico College · USUniversity of Glasgow · GB

Funding

WOMEN'S CANCERS RESEARCH PROGRAMP30CA118100 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Yolanda Sanchez · 2005 to 2026
$57.1M
UNM TRAININGP50GM085273 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI LIDKE, KEITH A · 2009 to 2018
$26.1M
Phase II of BUILDing SCHOLARSUL1GM118970 · NIGMS · UNIVERSITY OF TEXAS EL PASO · PI ALEY, STEPHEN B, BOLAND, THOMAS · 2015 to 2023
$17.9M
Phase II of BUILDing SCHOLARS - Research Enrichment CoreRL5GM118969 · NIGMS · UNIVERSITY OF TEXAS EL PASO · PI ALEY, STEPHEN B, BOLAND, THOMAS · 2015 to 2023
$7.4M
The role of PKCtheta in T cell and T-ALL migrationR01AI097202 · NIAID · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI CANNON, JUDY LIN · 2012 to 2016
$1.9M
BUILDing SCHOLARS (Research Enrichment Core)RL5MD009592 · NIMHD · UNIVERSITY OF TEXAS EL PASO · PI AGUILERA, RENATO J, ALEY, STEPHEN B · 2014 to 2014
$268k
Chief Scientist Office ETM/374Chief Scientist Office SCD/08NCI NIH HHS P30 CA118100NIAID NIH HHS R01 AI097202NIGMS NIH HHS P50 GM085273NIGMS NIH HHS RL5 GM118969NIGMS NIH HHS UL1 GM118970NIMHD NIH HHS RL5 MD009592
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCARD Signaling Adaptor ProteinsCell Line, TumorCell MovementCentral Nervous SystemChildGuanylate CyclaseHeterograftsHumansMiceNeoplasm InvasivenessPrecursor T-Cell Lymphoblastic Leukemia-LymphomaTransduction, GeneticCARD11 protein, humanCARD Signaling Adaptor ProteinsGuanylate Cyclase

Identifiers

PMID27698445
PMCPMC5218581
OpenAlexW2527929803

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.