Evidence map›Paper›PMID 27698264›Full record

ArticleIntegrative cancer therapies2017

Antitumor Activity of the Chinese Medicine JC-001 Is Mediated by Immunomodulation in a Murine Model of Hepatocellular Carcinoma.

Meng-Hsien Chuang, Jinghua Tsai Chang, Li-Jin Hsu, Ming-Shiou Jan, Fung-Jou Lu

Open access · goldAbstract read
In one paragraph

Article in Integrative cancer therapies, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Using Traditional Chinese Medicine to Treat Hepatocellular Carcinoma by Targeting Tumor Immunity.Evidence-based complementary and alternative medicine : eCAM · 2020
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Meng-Hsien Chuang1 Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Jinghua Tsai Chang1 Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Li-Jin Hsu3 Department of Medical Laboratory Science and Technology, Medical College, National Cheng Kung University, Tainan, Taiwan.
Ming-Shiou Jan4 Institute of Biochemistry, Microbiology and Immunology, Chung Shan Medical University, Taichung, Taiwan.
Fung-Jou Lu1 Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Chung Shan Medical University · TWChung Shan Medical University Hospital · TWNational Cheng Kung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

JC-001 is a Chinese medicine that has been used to treat liver disease; however, its significance in cancer treatment has not been characterized. In this study, we used an immunocompetent tumor model to characterize the antitumor activity of JC-001. A total of 48 Hepa 1-6 tumor-bearing C57BL/6 mice were randomly grouped into 4 groups and treated with H

Indexed as

AnimalsAntineoplastic AgentsCarcinoma, HepatocellularCell LineCell Line, TumorCell ProliferationDisease Models, AnimalDrugs, Chinese HerbalFemaleHep G2 CellsHMGB ProteinsHumansImmunomodulationLiver NeoplasmsMaleMiceAntineoplastic AgentsDrugs, Chinese HerbalHMGB ProteinsRNA, MessengerChinese medicinecocultureHepa 1-6hepatocellular carcinomaimmunomodulationJC-001splenocytes

Identifiers

PMID27698264
PMCPMC5739137
OpenAlexW2528992600

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.