ArticleDevelopment (Cambridge, England)2016
Demethylation of ERECTA receptor genes by IBM1 histone demethylase affects stomatal development.
Article in Development (Cambridge, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 35 citations in OpenAlex.
- Regulation of stomatal development by receptor-like kinases and receptor-like proteins inFrontiers in plant science · 2026Review
- Genome-Wide Characterization and Expression Profile of the Jumonji-C Family Genes inInternational journal of molecular sciences · 2025Article
- Transcription factors WOX11 and LBD16 function with histone demethylase JMJ706 to control crown root development in rice.The Plant cell · 2024Article
- MAPK Cascades in Plant Microbiota Structure and Functioning.Journal of microbiology (Seoul, Korea) · 2024Review
- Altering Stomatal Density for Manipulating Transpiration and Photosynthetic Traits in Rice through CRISPR/Cas9 Mutagenesis.Current issues in molecular biology · 2023Article
- Involvement of 5mC DNA demethylationForestry research · 2023Article
- Dysfunction of histone demethylase IBM1 in Arabidopsis causes autoimmunity and reshapes the root microbiome.The ISME journal · 2022Article
- Genome-wide identification and expression analysis of JmjC domain-containing genes in grape under MTA treatment.Functional & integrative genomics · 2022Article
- Histone demethylase IBM1-mediated meiocyte gene expression ensures meiotic chromosome synapsis and recombination.PLoS genetics · 2022Article
- Unravelling the Role of Epigenetic Modifications in Development and Reproduction of Angiosperms: A Critical Appraisal.Frontiers in genetics · 2022Review
- Epigenome plasticity in plants.Nature reviews. Genetics · 2022Review
- Machine learning-enabled phenotyping for GWAS and TWAS of WUE traits in 869 field-grown sorghum accessions.Plant physiology · 2021Article
- The Dynamism of Transposon Methylation for Plant Development and Stress Adaptation.International journal of molecular sciences · 2021Review
- Agave angustifolia albino plantlets lose stomatal physiology function by changing the development of the stomatal complex due to a molecular disruption.Molecular genetics and genomics : MGG · 2020Article
- Article
- SPEECHLESS Speaks Loudly in Stomatal Development.Frontiers in plant science · 2020Review
- Article
- Dynamics and function of DNA methylation in plants.Nature reviews. Molecular cell biology · 2018Review
- UTR-Dependent Control of Gene Expression in Plants.Trends in plant science · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
DNA methylation and histone modifications interact to modulate gene expression in biological organisms. The histone demethylase IBM1 suppresses DNA methylation and gene silencing, primarily by targeting genic regions in the Arabidopsis genome. The chromatin regulator EDM2 is also required for prevention of genic DNA methylation because it maintains IBM1 expression by promoting IBM1 mRNA distal polyadenylation. Loss-of-function ibm1 and edm2 mutant plants display a wide range of developmental defects, but little is known about which developmentally important genes are regulated by IBM1 and EDM2. Here, we show that both ibm1 and edm2 mutants display defects in production of stomatal lineage cells, which is linked to DNA hypermethylation of the ERECTA family genes, including ER, ERL1 and ERL2 Stomatal phenotypes and DNA methylation levels of ER genes in ibm1 and edm2 mutants are restored by mutations in the genes encoding the histone methyltransferase KYP and DNA methyltransferase CMT3. Our data demonstrate that a specific plant developmental context is influenced by IBM1-regulated histone modification and DNA methylation on the gene body region of the ERECTA receptors.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.