ArticleThe Plant cell2016
Spatial Regulation of ABCG25, an ABA Exporter, Is an Important Component of the Mechanism Controlling Cellular ABA Levels.
Article in The Plant cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 66 citations in OpenAlex.
- Beyond membrane transport: Transporters as dynamic signal integrators for plant signaling and adaptation.Plant communications · 2026Review
- Comprehensive Analysis of OsENTH Genes and Functional Characterization in Rice Pollen Germination and Pollen Tube Growth.Rice (New York, N.Y.) · 2026Article
- BAM1/2-mediated phosphorylation of ABCG16 reduces its stability and ABA export activity to suppress root growth in Arabidopsis.Plant communications · 2025Article
- Salicylic acid: new pathways arising?Frontiers in plant science · 2025Review
- Computational Reconstruction of the Transcription Factor Regulatory Network Induced by Auxin inPlants (Basel, Switzerland) · 2024Article
- Genome-wide identification and expression analysis ofFrontiers in genetics · 2024Article
- Expression and localization of two β-carbonic anhydrases inFrontiers in plant science · 2024Article
- Cryo-EM structure and molecular mechanism of abscisic acid transporter ABCG25.Nature plants · 2023Article
- Transcriptome analysis of response strategy in Hemerocallis fulva under drought stress.Genes & genomics · 2023Article
- A metabolic perspective of selection for fruit quality related to apple domestication and improvement.Genome biology · 2023Article
- Membrane Proteins in Plant Salinity Stress Perception, Sensing, and Response.The Journal of membrane biology · 2023Review
- Variations in Circadian Clock Organization & Function: A Journey from Ancient to Recent.Planta · 2022Review
- AP1/2β-mediated exocytosis of tapetum-specific transporters is required for pollen development in Arabidopsis thaliana.The Plant cell · 2022Article
- Inter-tissue and inter-organ signaling in drought stress response and phenotyping of drought tolerance.The Plant journal : for cell and molecular biology · 2022Review
- Genetic dissection of maize seedling traits in an IBM Syn10 DH population under the combined stress of lead and cadmium.Molecular genetics and genomics : MGG · 2021Article
- Cold stress triggers premature fruit abscission through ABA-dependent signal transduction in early developing apple.PloS one · 2021Article
- Leaf-derived ABA regulates rice seed development via a transporter-mediated and temperature-sensitive mechanism.Science advances · 2021Article
- Plant Cells under Attack: Unconventional Endomembrane Trafficking during Plant Defense.Plants (Basel, Switzerland) · 2020Review
- Drought Stress Responses and Resistance in Plants: From Cellular Responses to Long-Distance Intercellular Communication.Frontiers in plant science · 2020Review
- Low Water Potential and At14a-Like1 (AFL1) Effects on Endocytosis and Actin Filament Organization.Plant physiology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The phytohormone abscisic acid (ABA) plays crucial roles in various physiological processes, including responses to abiotic stresses, in plants. Recently, multiple ABA transporters were identified. The loss-of-function and gain-of-function mutants of these transporters show altered ABA sensitivity and stomata regulation, highlighting the importance of ABA transporters in ABA-mediated processes. However, how the activity of these transporters is regulated remains elusive. Here, we show that spatial regulation of ATP BINDING CASETTE G25 (ABCG25), an ABA exporter, is an important mechanism controlling its activity. ABCG25, as a soluble green fluorescent protein (sGFP) fusion, was subject to posttranslational regulation via clathrin-dependent and adaptor protein complex-2-dependent endocytosis followed by trafficking to the vacuole. The levels of sGFP:ABCG25 at the plasma membrane (PM) were regulated by abiotic stresses and exogenously applied ABA; PM-localized sGFP:ABCG25 decreased under abiotic stress conditions via activation of endocytosis in an ABA-independent manner, but increased upon application of exogenous ABA via activation of recycling from early endosomes in an ABA-dependent manner. Based on these findings, we propose that the spatial regulation of ABCG25 is an important component of the mechanism by which plants fine-tune cellular ABA levels according to cellular and environmental conditions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.