ArticleBiomaterials2016
Regenerated silk materials for functionalized silk orthopedic devices by mimicking natural processing.
Article in Biomaterials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 59 citations in OpenAlex.
- Nano-to-macroscale dual core-shell structured bioartificial ligament improves outcomes of anterior cruciate ligament reconstruction in rats: A proof-of-concept study.Bioactive materials · 2026Article
- A strategy for biomass-derived matrix with facile moulding and closed-loop recycling capabilities.Nature communications · 2026Article
- Tuning the Biodegradation Rate of Silk Materials via Embedded Enzymes.ACS biomaterials science & engineering · 2024Article
- Exploring microRNAs in craniofacial regenerative medicine.Biochemical Society transactions · 2023Review
- Controllable Production of Natural Silk Nanofibrils for Reinforcing Silk-Based Orthopedic Screws.Polymers · 2023Article
- Advanced silk materials for musculoskeletal tissue regeneration.Frontiers in bioengineering and biotechnology · 2023Review
- Localized, on-demand, sustained drug delivery from biopolymer-based materials.Expert opinion on drug delivery · 2022Article
- 3D Printing of Monolithic Proteinaceous Cantilevers Using Regenerated Silk Fibroin.Molecules (Basel, Switzerland) · 2022Article
- Fiber-Based Biopolymer Processing as a Route toward Sustainability.Advanced materials (Deerfield Beach, Fla.) · 2022Review
- Silk reservoir implants for sustained drug delivery.ACS applied bio materials · 2021Article
- From Silk Spinning to 3D Printing: Polymer Manufacturing using Directed Hierarchical Molecular Assembly.Advanced healthcare materials · 2020Review
- The Mechanical Properties, Secondary Structure, and Osteogenic Activity of Photopolymerized Fibroin.Polymers · 2020Article
- Engineering Silk Materials: From Natural Spinning to Artificial Processing.Applied physics reviews · 2020Article
- Silk Polymers and Nanoparticles: A Powerful Combination for the Design of Versatile Biomaterials.Frontiers in chemistry · 2020Review
- Thermoplastic moulding of regenerated silk.Nature materials · 2020Article
- Nanoscale optical and structural characterisation of silk.Beilstein journal of nanotechnology · 2019Article
- Silk Biomaterials-Mediated miRNA Functionalized Orthopedic Devices.Tissue engineering. Part A · 2019Article
- Ionic Liquid-Assisted Synthesis of Mesoporous Silk Fibroin/Silica Hybrids for Biomedical Applications.ACS omega · 2018Article
- Coding cell micropatterns through peptide inkjet printing for arbitrary biomineralized architectures.Advanced functional materials · 2018Article
- Materials-by-Design: Computation, Synthesis, and Characterization from Atoms to Structures.Physica scripta · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
Silk fibers spun by silkworms and spiders exhibit exceptional mechanical properties with a unique combination of strength, extensibility and toughness. In contrast, the mechanical properties of regenerated silk materials can be tuned through control of the fabrication process. Here we introduce a biomimetic, all-aqueous process, to obtain bulk regenerated silk-based materials for the fabrication of functionalized orthopedic devices. The silk materials generated in the process replicate the nano-scale structure of natural silk fibers and possess excellent mechanical properties. The biomimetic materials demonstrate excellent machinability, providing a path towards the fabrication of a new family of resorbable orthopedic devices where organic solvents are avoided, thus allowing functionalization with bioactive molecules to promote bone remodeling and integration.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.