Trial reportJournal of the American Society of Hypertension : JASH2016
The association between Self-Reported Medication Adherence scores and systolic blood pressure control: a SPRINT baseline data study.
Trial report in Journal of the American Society of Hypertension : JASH, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Self-Reported Medication Adherence Measured With Morisky Medication Adherence Scales and Its Determinants in Hypertensive Patients Aged ≥60 Years: A Systematic Review and Meta-Analysis.Frontiers in pharmacology · 2019Pooled it
- Fluctuations in adherence to antihypertensive medication and cardiovascular outcomes: a secondary analysis of the SPRINT trial.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Trial
- Blood Pressure Association with the 8-Item Morisky Medication Adherence Scale in Hypertensive Adults from Low-Resource Primary Care Settings: Results from a Prospective Cohort Nested within a Randomised Controlled Trial.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2023Trial
- Is Medication Adherence Predictive of Cardiovascular Outcomes and Blood Pressure Control? The Systolic Blood Pressure Intervention Trial (SPRINT).American journal of hypertension · 2022Trial
- Assessment of Long-term Benefit of Intensive Blood Pressure Control on Residual Life Span: Secondary Analysis of the Systolic Blood Pressure Intervention Trial (SPRINT).JAMA cardiology · 2020Trial
- Article
- Association Between Self-Reported Medication Adherence and Therapeutic Inertia in Hypertension: A Secondary Analysis of SPRINT (Systolic Blood Pressure Intervention Trial).Journal of the American Heart Association · 2024Article
- Blood pressure control and its associated factors among patients with heart failure in Jordan.Journal of human hypertension · 2023Article
- Association of adherence measured by self-reported pill count with achieved blood pressure level in hypertension patients: a cross-sectional study.Clinical hypertension · 2022Article
- Clinical characteristics of older adults with hypertension and unrecognized cognitive impairment.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Article
- Self-Reported Race as a Social Determinant of Stroke Risk in Observational Versus Clinical Trial Datasets.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022Observational
- Persistence of drug therapy is associated with ischemic stroke and other vascular events in high-risk stroke population.Frontiers in neurology · 2022Article
- Prevalence, predictors, and outcomes of both true- and pseudo-resistant hypertension in the action to control cardiovascular risk in diabetes trial: a cohort study.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Article
- Association between adherence to antihypertensive medications and health outcomes in middle and older aged community dwelling adults; results from the Irish longitudinal study on ageing.European journal of clinical pharmacology · 2019Article
- Medication Adherence In Patients With Arterial Hypertension: The Relationship With Healthcare Systems' Organizational Factors.Patient preference and adherence · 2019Article
- Prevalence of Nephrolithiasis in Patients with Chronic Liver Disease: A Case-Control Study.Journal of clinical and experimental hepatology · 2018Article
- Personalized behavior change program for glaucoma patients with poor adherence: a pilot interventional cohort study with a pre-post design.Pilot and feasibility studies · 2018Article
- Adherence to riluzole in patients with amyotrophic lateral sclerosis: an observational study.Neuropsychiatric disease and treatment · 2018Article
- Cost-Effectiveness of Intensive versus Standard Blood-Pressure Control.The New England journal of medicine · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
Abstract
We examined baseline data from the Systolic Blood Pressure Intervention Trial (SPRINT) to investigate whether medication adherence, measured by the 8-item Morisky Medication Adherence Scale (MMAS-8), was associated with systolic blood pressure (SBP) and whether MMAS-8 score and number of antihypertensive medications interacted in influencing SBP. A total of 8435 SPRINT participants were included: 21.2% had low adherence (MMAS-8: <6); 40.0% had medium adherence (6 to <8); and 38.8% had high adherence (8). SBP was <140 mm Hg in 54.6%; 140-160 mm Hg in 36.6%; and >160 mm Hg in 8.8%. In multivariable regression, medium vs. low adherence weakly associated with lower SBP (odds ratio: 1.17; confidence interval: 1.04, 1.31). SPRINT eligibility criteria should be considered when interpreting results. Efforts to understand and enhance adherence are crucial to improve population health, and using self-report instruments might be considered for predicting treatment adherence and response in future efficacy trials and for identifying patients for adherence support in clinical practice.
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