Evidence map›Paper›PMID 27697219›Full record

ArticlePlacenta2016

A new biological and clinical resource for research into pregnancy complications: The Baby Bio Bank.

Lydia J Leon, Nita Solanky, Susanne E Stalman, Charalambos Demetriou, Sayeda Abu-Amero, Philip Stanier, Lesley Regan, Gudrun E Moore

Open access · hybridAbstract read
In one paragraph

Article in Placenta, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Emerging phenotypes linked to variants inFrontiers in endocrinology · 2022
    Article
  3. Article
  4. Article
  5. Analysis ofF1000Research · 2019
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Lydia J LeonUCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, United Kingdom. Electronic address: lydia.leon.11@ucl.ac.uk.
Nita SolankyUCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, United Kingdom.
Susanne E StalmanAcademic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
Charalambos DemetriouUCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, United Kingdom.
Sayeda Abu-AmeroUCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, United Kingdom.
Philip StanierUCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, United Kingdom.
Lesley ReganObstetrics and Gynaecology Department, St Mary's Hospital, Imperial College, Praed Street, London W2 1NY, United Kingdom.
Gudrun E MooreUCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, United Kingdom.
University College London · GBAmsterdam UMC Location University of Amsterdam · NLInstitute of Child Health · GRSt Mary's Hospital · GB

Funding

Department of HealthMedical Research Council G0801438
6 · The paper itself

Abstract

About 20% of pregnancies are affected by some form of complication. Research has shown that anomalies in implantation, development, and growth of the fetus; ineffective nutrient exchange between mother and fetus due to placental dysfunction; and maternal problems such as hypertension or infection during pregnancy can all lead to adverse pregnancy outcomes. However, the molecular aetiology of such events remains poorly understood. Fetal growth restriction (FGR), recurrent miscarriage (RM), preterm birth (PTB), and pre-eclampsia (PE) are the most common pregnancy complications encountered in the UK and these outcomes can result in an array of morbidities in both mother and baby, and in the most severe cases in mortality. We need to know more about normal pregnancy and where the important triggers are for failure. This prompted us to collect a large set of biological samples with matching clinical data from over 2500 normal and abnormal pregnancies, for use in research into these conditions. This paper outlines the nature of these sample sets and their availability to academia and industry, with the intention that their widespread use in research will make significant contributions to the improvement of maternal and fetal health worldwide (http://www.ucl.ac.uk/tapb/sample-and-data-collections-at-ucl/biobanks-ucl/baby-biobank).

Indexed as

Biological Specimen BanksDatabases as TopicPregnancy ComplicationsFemaleHumansPregnancySpecimen HandlingBiobankFetal growth restrictionMiscarriagePre-eclampsiaPregnancy complicationsPreterm birth

Identifiers

PMID27697219
PMCPMC5062948
OpenAlexW2514615451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.