Evidence map›Paper›PMID 27697084›Full record

ArticleInfection control and hospital epidemiology2017

Environmental Exposures and the Risk of Central Venous Catheter Complications and Readmissions in Home Infusion Therapy Patients.

Sara C Keller, Deborah Williams, Mitra Gavgani, David Hirsch, John Adamovich, Dawn Hohl, Amanda Krosche, Sara Cosgrove, Trish M Perl

Abstract readMulticenter Study
In one paragraph

Article in Infection control and hospital epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Article
  6. Article
  7. Article
  8. SINPE Position Paper on the use of home parenteral nutrition in cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Observational
  17. Article
  18. Rates of and Risk Factors for Adverse Drug Events in Outpatient Parenteral Antimicrobial Therapy.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018
    Article
  19. Article
  20. It's Complicated: Patient and Informal Caregiver Performance of Outpatient Parenteral Antimicrobial Therapy-Related Tasks.American journal of medical quality : the official journal of the American College of Medical Quality
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Sara C Keller1Division of Infectious Diseases,Department of Medicine,Johns Hopkins University School of Medicine,Baltimore,Maryland.
Deborah Williams2Johns Hopkins Home Care Group,Baltimore,Maryland.
Mitra Gavgani2Johns Hopkins Home Care Group,Baltimore,Maryland.
David Hirsch2Johns Hopkins Home Care Group,Baltimore,Maryland.
John Adamovich2Johns Hopkins Home Care Group,Baltimore,Maryland.
Dawn Hohl2Johns Hopkins Home Care Group,Baltimore,Maryland.
Amanda Krosche1Division of Infectious Diseases,Department of Medicine,Johns Hopkins University School of Medicine,Baltimore,Maryland.
Sara Cosgrove1Division of Infectious Diseases,Department of Medicine,Johns Hopkins University School of Medicine,Baltimore,Maryland.
Trish M Perl1Division of Infectious Diseases,Department of Medicine,Johns Hopkins University School of Medicine,Baltimore,Maryland.
Johns Hopkins University · USJohns Hopkins Medicine · US

Funding

Institute for Clinical and Translational ResearchKL2TR001077 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$9.2M
Institute for Clinical and Translational ResearchKL2TR000425 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2012 to 2012
$0k
ACL HHS U54CK000447NCATS NIH HHS KL2 TR000425NCATS NIH HHS KL2 TR001077NCEZID CDC HHS U54 CK000447
6 · The paper itself

Abstract

BACKGROUND Patients are frequently discharged with central venous catheters (CVCs) for home infusion therapy. OBJECTIVE To study a prospective cohort of patients receiving home infusion therapy to identify environmental and other risk factors for complications. DESIGN Prospective cohort study between March and December 2015. SETTING Home infusion therapy after discharge from academic medical centers. PARTICIPANTS Of 368 eligible patients discharged from 2 academic hospitals to home with peripherally inserted central catheters and tunneled CVCs, 222 consented. Patients remained in the study until 30 days after CVC removal. METHODS Patients underwent chart abstraction and monthly telephone surveys while the CVC was in place, focusing on complications and environmental exposures. Multivariable analyses estimated adjusted odds ratios and adjusted incident rate ratios between clinical, demographic, and environmental risk factors and 30-day readmissions or CVC complications. RESULTS Of 222 patients, total parenteral nutrition was associated with increased 30-day readmissions (adjusted odds ratio, 4.80 [95% CI, 1.51-15.21) and CVC complications (adjusted odds ratio, 2.41 [95% CI, 1.09-5.33]). Exposure to soil through gardening or yard work was associated with a decreased likelihood of readmissions (adjusted odds ratio, 0.09 [95% CI, 0.01-0.74]). Other environmental exposures were not associated with CVC complications. CONCLUSIONS complications and readmissions were common and associated with the use of total parenteral nutrition. Common environmental exposures (well water, cooking with raw meat, or pets) did not increase the rate of CVC complications, whereas soil exposures were associated with decreased readmissions. Interventions to decrease home CVC complications should focus on total parenteral nutrition patients. Infect Control Hosp Epidemiol 2016;1-8.

Indexed as

AdultAgedBaltimoreCatheterization, Central VenousCentral Venous CathetersEnvironmental ExposureFemaleHome Infusion TherapyHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisParenteral Nutrition, TotalPatient ReadmissionProspective Studies

Identifiers

PMID27697084
PMCPMC5502130
OpenAlexW2529570697

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.