Evidence map›Paper›PMID 27696908›Full record

ReviewCritical reviews in biochemistry and molecular biology

Decoding P4-ATPase substrate interactions.

Bartholomew P Roland, Todd R Graham

Abstract readReview
In one paragraph

Review in Critical reviews in biochemistry and molecular biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Lipid Transport byInfection and immunity · 2022
    Article
  10. Article
  11. Biallelic truncating variants inJournal of medical genetics · 2022
    Article
  12. Article
  13. Article
  14. Review
  15. mBio · 2021
    Article
  16. Article
  17. Article
  18. Review
  19. Conserved mechanism of phospholipid substrate recognition by the P4-ATPase Neo1 from Saccharomyces cerevisiae.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Bartholomew P Rolanda Department of Biological Sciences , Vanderbilt University , 1161 21st Ave South , Nashville , TN , USA.
Todd R Grahama Department of Biological Sciences , Vanderbilt University , 1161 21st Ave South , Nashville , TN , USA.

Funding

Program in NeurogenomicsT32MH065215 · NIMH · VANDERBILT UNIVERSITY · PI ROGER J COLBRAN · 2002 to 2026
$6.4M
P4-ATPase mechanism of phospholipid translocationR01GM107978 · NIGMS · VANDERBILT UNIVERSITY · PI GRAHAM, TODD R · 2013 to 2021
$2.5M
Molecular Characterization of the Phospholipid Flippase Substrate PathwayF32GM116310 · NIGMS · VANDERBILT UNIVERSITY · PI ROLAND, BARTHOLOMEW P · 2015 to 2016
$109k
NIGMS NIH HHS F32 GM116310NIGMS NIH HHS R01 GM107978NIMH NIH HHS T32 MH065215
6 · The paper itself

Abstract

Cellular membranes display a diversity of functions that are conferred by the unique composition and organization of their proteins and lipids. One important aspect of lipid organization is the asymmetric distribution of phospholipids (PLs) across the plasma membrane. The unequal distribution of key PLs between the cytofacial and exofacial leaflets of the bilayer creates physical surface tension that can be used to bend the membrane; and like Ca

Indexed as

Adenosine TriphosphatasesAnimalsCell MembraneHumansModels, MolecularPhospholipidsPhospholipid Transfer ProteinsProtein DomainsSubstrate SpecificityAdenosine TriphosphatasesPhospholipidsPhospholipid Transfer Proteinsmembrane asymmetrymembrane biologyP4-ATPasephospholipid flippasephospholipid transportprotein engineering

Identifiers

PMID27696908
PMCPMC5285478

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.