ReviewInternational wound journal2017
Use of negative pressure wound therapy on malignant wounds - a case report and review of literature.
Review in International wound journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 27 citations in OpenAlex.
- Negative Pressure Wound Therapy in an Immunocompromised Child: A Case Report From a Resource-Limited Setting in Ghana.Clinical case reports · 2026Article
- [Clinical diagnosis and treatment strategies for malignant complex wounds].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2025Review
- Therapeutic Management of Malignant Wounds: An Update.Current treatment options in oncology · 2024Review
- Advanced Bionic Attachment Equipment Inspired by the Attachment Performance of Aquatic Organisms: A Review.Biomimetics (Basel, Switzerland) · 2023Review
- Negative Pressure Wound Therapy in the Head and Neck: A Summary of Uses and Application Techniques.Seminars in plastic surgery · 2023Review
- A Case of Malignant Transformation of Solitary Recurrent Cylindroma on Scalp.Annals of dermatology · 2022Article
- [Clinical application and related research advances of negative pressure wound therapy in wound treatment].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2022Review
- Review
- Combined internal and external negative pressure wound therapy: breakthrough treatment for lymphocutaneous intractable fistula.Surgery today · 2021Article
- Negative Pressure Wound Therapy: Mechanism of Action and Clinical Applications.Seminars in plastic surgery · 2021Review
- Negative Pressure Wound Therapy in Malignancy: Always an Absolute Contraindication?Plastic and reconstructive surgery. Global open · 2020Article
- [An uncommon skin tumor in the emergency department].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2018Article
- A Novel Tube-Drainage Technique of Negative Pressure Wound Therapy for Fistulae after Reconstructive Surgery.Plastic and reconstructive surgery. Global open · 2018Article
- Use of controlled negative pressure in management of phlegmon caused by fulminant complication of pressure wound: A case report.Medicine · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The presence of malignancy is considered a contraindication to the use of negative pressure wound therapy (NPWT) because of concerns that it may promote tumourigenesis and expedite metastasis. This notion is extrapolated from studies evaluating NPWT in normal tissues. Despite the absence of direct evidence, the use of this technology in malignant wounds is widely considered a contraindication. We present the case of a patient with treatment-resistant metastatic colon cancer, who developed a chronic abdominal wound with positive margins. A staged reconstruction using NPWT was performed and wound closure allowed the patient to meet eligibility criteria and enrol in a clinical trial for treatment of his oncological disease. Skin closure remained intact until the patient expired 6 months after the wound closure. This case, as well as others in the literature, demonstrated that the use of NPWT should not be considered an absolute contraindication in malignancy. Individualised approaches taking into account the patient's clinical scenario, the available evidence, as well as the risks and benefits of this technology are recommended.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.