ReviewStem cell reviews and reports2016
The Role of Autophagy in the Maintenance of Stemness and Differentiation of Mesenchymal Stem Cells.
Review in Stem cell reviews and reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
52 citing papers in PubMed.
- Chemically Derived Hepatic Progenitors Are Reprogrammed through Autophagy Suppression by A83-01.International journal of stem cells · 2026Article
- Chitosan-rapamycin carbon dots rejuvenate autologous Sca-1⁺ stem cells paracrine function for neuroprotection in normal tension glaucoma.Stem cell research & therapy · 2026Article
- Evaluation of the Osteogenic Potential of Apigenin via Inducing Autophagy: An In Vitro Study.Stem cells international · 2026Article
- Autophagy-driven modulation of stem cell dynamics inVirulence · 2025Article
- Drug Repurposing of Selected Antibiotics: An Emerging Approach in Cancer Drug Discovery.ACS omega · 2024Review
- A negative feedback loop underlies the Warburg effect.NPJ systems biology and applications · 2024Article
- Regulation Mechanisms and Maintenance Strategies of Stemness in Mesenchymal Stem Cells.Stem cell reviews and reports · 2024Review
- Article
- Novel perspectives on autophagy-oxidative stress-inflammation axis in the orchestration of adipogenesis.Frontiers in endocrinology · 2024Review
- Azithromycin, a potent autophagy inhibitor for cancer therapy, perturbs cytoskeletal protein dynamics.British journal of cancer · 2023Article
- Ginsenoside Rg2 Promotes the Proliferation and Stemness Maintenance of Porcine Mesenchymal Stem Cells through Autophagy Induction.Foods (Basel, Switzerland) · 2023Article
- Identification and validation of autophagy-related genes during osteogenic differentiation of bone marrow mesenchymal stem cells.Iranian journal of basic medical sciences · 2022Article
- Ferutinin induces osteoblast differentiation of DPSCs via induction of KLF2 and autophagy/mitophagy.Cell death & disease · 2022Article
- MSCs interaction with the host lung microenvironment: An overlooked aspect?Frontiers in immunology · 2022Review
- Proteomic Analysis of Exosomes Secreted from Human Alpha-1 Antitrypsin Overexpressing Mesenchymal Stromal Cells.Biology · 2021Article
- Myelodysplastic Syndromes and Metabolism.International journal of molecular sciences · 2021Review
- Autophagy controls mesenchymal stem cell therapy in psychological stress colitis mice.Autophagy · 2021Article
- The Phosphonate Derivative of CInternational journal of molecular sciences · 2021Article
- The mitochondrial fission factor FIS1 promotes stemness of human lung cancer stem cells via mitophagy.FEBS open bio · 2021Article
- Neuroprotection offered by mesenchymal stem cells in perinatal brain injury: Role of mitochondria, inflammation, and reactive oxygen species.Journal of neurochemistry · 2021Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Regulated self-consumption, also known as autophagy, is an evolutionary conserved process that degrades cellular components by directing them to the lysosomal compartment of eukaryotic cells. As a major intracellular degradation and recycling pathway, autophagy is crucial for maintaining and remodeling cellular homeostasis during normal cellular and tissue development. Recent studies have demonstrated that autophagy is necessary for the maintenance of cellular stemness and for a number of differentiation processes, including the lineage determination of mesenchymal stem cells. These are multipotent progenitor cells with self-renewal capacities that can give rise to a subset of tissues and thus hold a consistent potential in regenerative medicine. Here, we review the current literature on the complex liaison between autophagy induced by various extra- or intracellular stimuli and the molecular targets that affect mesenchymal stem cells proliferation and differentiation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.