Evidence map›Paper›PMID 27696182›Full record

ArticleJournal of autism and developmental disorders2016

Mapping the Network of Neuropsychological Impairment in Children with Autism Spectrum Disorder: A Graph Theoretical Analysis.

George M Ibrahim, Benjamin R Morgan, Vanessa M Vogan, Rachel C Leung, Evdokia Anagnostou, Margot J Taylor

Abstract read
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In one paragraph

Article in Journal of autism and developmental disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Drug development for Autism Spectrum Disorder (ASD): Progress, challenges, and future directions.European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2021
    Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

George M IbrahimDivision of Neurosurgery, Department of Surgery, Hospital for Sick Children, University of Toronto, Suite 1403, 555 University Ave, Toronto, ON, M5G 1X8, Canada. george.m.ibrahim@gmail.com.
Benjamin R MorganDepartment of Diagnostic Imaging, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.
Vanessa M VoganDepartment of Psychology, University of Toronto, Toronto, ON, Canada.
Rachel C LeungDepartment of Psychology, University of Toronto, Toronto, ON, Canada.
Evdokia AnagnostouDivision of Neurology, Holland Bloodview Centre, University of Toronto, Toronto, ON, Canada.
Margot J TaylorDepartment of Psychology, University of Toronto, Toronto, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Children with autism spectrum disorder (ASD) exhibit social-communicative impairments. Less is known about the neuropsychological profile of ASD, although cognitive and neuropsychological deficits are evident. We modelled neuropsychological function in 20 children with ASD and 20 sex, age and IQ matched typically-developing controls (ages 7-14) as a network of interacting parameters. Graph theoretical analysis was applied to identify critical topographic regions within this network. Two areas were significantly stronger hubs in typically-developing children, the ability to shift attention (p < 0.001) and overall executive function (p < 0.001). Planning/organization was a stronger hub in the cognitive networks of children with ASD (p = 0.001). We show that ASD is not only characterized by impairments in various neurocognitive domains, but also alterations in their interaction.

Indexed as

Models, PsychologicalAttentionAutism Spectrum DisorderBrain MappingCase-Control StudiesChildExecutive FunctionFemaleHumansMalePropensity ScoreSocial Communication DisorderASDGraph theoryNetwork analysis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.