Evidence map›Paper›PMID 27696176›Full record

ArticleJournal of autism and developmental disorders2017

Neural Basis of Visual Attentional Orienting in Childhood Autism Spectrum Disorders.

Eric R Murphy, Megan Norr, John F Strang, Lauren Kenworthy, William D Gaillard, Chandan J Vaidya

Open access · greenAbstract read
In one paragraph

Article in Journal of autism and developmental disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Eric R MurphyDepartment of Psychiatry, Washington University in St. Louis, 4444 Forest Park Parkway, Suite 2100, St Louis, MO, 63108, USA. murphye@psychiatry.wustl.edu.
Megan NorrDepartment of Psychology, University of California, Berkley, Berkley, USA.
John F StrangChildren's Research Institute, Children's National Medical Center, Washington, USA.
Lauren KenworthyChildren's Research Institute, Children's National Medical Center, Washington, USA.
William D GaillardChildren's Research Institute, Children's National Medical Center, Washington, USA.
Chandan J VaidyaChildren's Research Institute, Children's National Medical Center, Washington, USA.
Children's National · USWashington University in St. Louis · US

Funding

NEUROIMAGING COREP30HD040677 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI VITTORIO GALLO, VITTORIO GALLO VITTORIO GALLO · 2001 to 2015
$15.9M
Research_ProjectU54HD090257 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI GUAY-WOODFORD, LISA MARIE · 2016 to 2020
$5.9M
Developmental Neuroscience and Child PsychopathologyT32MH100019 · NIMH · WASHINGTON UNIVERSITY · PI Deanna Barch, JOAN L. LUBY · 2013 to 2026
$4.8M
Neuroimaging of Top-Down Control and Bottom-Up Processes in Childhood ASDR01MH084961 · NIMH · GEORGETOWN UNIVERSITY · PI VAIDYA, CHANDAN J · 2009 to 2013
$2.1M
NICHD NIH HHS P30 HD040677NICHD NIH HHS U54 HD090257NIMH NIH HHS R01 MH084961NIMH NIH HHS T32 MH100019
6 · The paper itself

Abstract

We examined spontaneous attention orienting to visual salience in stimuli without social significance using a modified Dot-Probe task during functional magnetic resonance imaging in high-functioning preadolescent children with Autism Spectrum Disorder (ASD) and age- and IQ-matched control children. While the magnitude of attentional bias (faster response to probes in the location of solid color patch) to visually salient stimuli was similar in the groups, activation differences in frontal and temporoparietal regions suggested hyper-sensitivity to visual salience or to sameness in ASD children. Further, activation in a subset of those regions was associated with symptoms of restricted and repetitive behavior. Thus, atypicalities in response to visual properties of stimuli may drive attentional orienting problems associated with ASD.

Indexed as

Task Performance and AnalysisAttentional BiasAutism Spectrum DisorderCase-Control StudiesChildFemaleHumansMagnetic Resonance ImagingMaleOrientationPhotic StimulationReaction TimeAttention orientingAutism spectrum disorderfMRIRestricted and repetitive behaviorVisual salience

Identifiers

PMID27696176
PMCPMC5225079
OpenAlexW2524850261

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.