ArticlePituitary2017
Pituitary abscess: clinical manifestations, diagnosis and treatment of 66 cases from a large pituitary center over 23 years.
Article in Pituitary, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
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Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.
- Pituitary abscess: a case report and systematic review of 488 cases.Orphanet journal of rare diseases · 2023Pooled it
- Review
- Meningoencephalitis and secondary pituitary abscess in a 16-year-old patient with gigantism.JCEM case reports · 2026Article
- Non-surgical management of pituitary abscess: Case series and literature review.Surgical neurology international · 2026Article
- Pituitary Abscess Syndrome in Ruminants: Nine Cases.Animals : an open access journal from MDPI · 2025Article
- Rare secondary pituitary abscess arising in a craniopharyngioma: A case report and literature review.Experimental and therapeutic medicine · 2025Article
- A Case of Pituitary Abscess and Multiple Cerebral Intracranial Aneurysms Related to Dental Caries.Cureus · 2025Article
- Secondary Pituitary Abscess Inside a Macroadenoma Complicated by Postoperative Hemorrhage and Reinfection: A Case Report.The American journal of case reports · 2025Article
- Usefulness of 3T split acquisition fast spin-echo diffusion-weighted imaging for differentiating pituitary abscess from other sellar cystic lesions: a preliminary study.Neuroradiology · 2025Article
- Fungal Sinusitis Spreading to the Sellar Region Mimicking a Pituitary Tumor: Case Report and Literature Review.Journal of fungi (Basel, Switzerland) · 2025Article
- An unusual case of primary pituitary abscess due to Corynebacterium pseudodiphtheriticum.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025Article
- Article
- A Case Report of Recurrent Primary Pituitary Abscess: Challenges in Diagnosis and Treatment.Endocrine, metabolic & immune disorders drug targets · 2025Article
- Pituitary abscess occurring 12 years after transsphenoidal surgery for Rathke's cleft cyst.Radiology case reports · 2024Article
- Hypopituitarism due to CNS Aspergillus Infection.Internal medicine (Tokyo, Japan) · 2024Article
- Pituitary abscess: a descriptive analysis of a series of 19 patients-a multi-center experience.European journal of medical research · 2024Article
- Primary Pituitary Abscess: Two Case Reports.Journal of neurological surgery reports · 2024Article
- Inflammatory and Infectious Disorders in Endocrine Pathology.Endocrine pathology · 2023Review
- Characteristics of inflammatory and infectious diseases of the pituitary gland in patients undergoing transsphenoidal surgery.Pituitary · 2023Article
- Pituitary Abscess: A General Retrospective Diagnosis.JCEM case reports · 2023Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePituitary abscess (PA) is rare and commonly described in case reports or small case series. This study aimed to better determine salient clinical manifestations related to the diagnosis and appropriate treatment of PA using by far the largest case series of this disease.
methodsA total of 6361 consecutive patients underwent surgery for pituitary diseases in Peking Union Medical College Hospital between January 1991 and December 2013. Among this cohort, sixty-six patients were diagnosed with PA based on both intraoperative findings and postoperative histopathological evidence.
resultsThe most common clinical presentation was anterior pituitary hypofunction (81.8 %), followed by common headache (69.7 %), diabetes insipidus (DI; 47.9 %), visual disturbances (45.5 %) and symptoms related to infection (43.9 %). Forty patients (66.7 %) showed typical rim enhancement after gadolinium injection on magnetic resonance imaging (MRI). Most patients (63 of 66, 95.5 %) underwent transsphenoidal surgery (TSS), and the remaining 3 patients (4.5 %) were treated with transcranial surgery (TC). After follow-up for 7.2 ± 4.9 years, PA was diminished in most patients (81.8 %), as demonstrated by post-operative MRI, and eight patients underwent at least one additional operation due to recurrence.
conclusionsFor patients with hypopituitarism and DI with rim enhancement on MRI, we should consider the possible diagnosis of PA. Proper use of antibiotics, complete drainage via surgery and hormone replacement for hypopituitarism are the key treatments for PA.
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