Evidence map›Paper›PMID 27696120›Full record

ArticleNeurochemical research2016

Role of Estradiol in the Regulation of Prolactin Secretion During Late Pregnancy.

Carlos Villegas-Gabutti, Gisela E Pennacchio, Graciela A Jahn, Marta Soaje

Abstract read
PubMed Publisher
In one paragraph

Article in Neurochemical research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Evidence for hyperprolactinemia in migraineurs: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Carlos Villegas-GabuttiLaboratorio de Reproducción y Lactancia, IMBECU-CONICET, Casilla de Correo 855, 5500, Mendoza, Argentina.
Gisela E PennacchioLaboratorio de Reproducción y Lactancia, IMBECU-CONICET, Casilla de Correo 855, 5500, Mendoza, Argentina.
Graciela A JahnLaboratorio de Reproducción y Lactancia, IMBECU-CONICET, Casilla de Correo 855, 5500, Mendoza, Argentina.
Marta SoajeLaboratorio de Reproducción y Lactancia, IMBECU-CONICET, Casilla de Correo 855, 5500, Mendoza, Argentina. msoaje@mendoza-conicet.gob.ar.
Instituto de Medicina y Biología Experimental de Cuyo · ARUniversidad Nacional de Cuyo · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Estrogen action is necessary for evidencing the stimulatory action of mifepristone and naloxone on prolactin (PRL) secretion during late pregnancy. Our aim is to determine the mechanism mediating this facilitator action of estrogens. To investigate the hypothalamic mechanisms involved in estrogen actions in PRL secretion at the end of pregnancy, we measured the effect of pretreatment with the estrogen antagonist tamoxifen on the expression of tyrosine hydroxylase (TH), hormone receptors (ERα and β, PRs, PRLR

Indexed as

AnimalsEstradiolEstrogen Receptor alphaEstrogen Receptor betaFemaleHypothalamus, MiddleMifepristoneNaloxonePregnancyPregnancy, AnimalProgesteroneProlactinRats, WistarReceptors, Opioid, kappaReceptors, Opioid, muReceptors, ProgesteroneEstradiolEstrogen Receptor alphaEstrogen Receptor betaMifepristoneNaloxoneProgesteroneProlactinReceptors, Opioid, kappaReceptors, Opioid, muReceptors, ProgesteroneReceptors, ProlactinTyrosine 3-MonooxygenaseEstradiolMifepristone or RU-486NaloxonePregnancyProlactinRatTyrosine hydroxylase

Identifiers

PMID27696120
OpenAlexW2525659808

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.