Evidence map›Paper›PMID 27695665›Full record

ArticleCurrent addiction reports2016

Alexithymia and Addiction: A Review and Preliminary Data Suggesting Neurobiological Links to Reward/Loss Processing.

Kristen P Morie, Sarah W Yip, Charla Nich, Karen Hunkele, Kathleen M Carroll, Marc N Potenza

Open access · greenAbstract read
In one paragraph

Article in Current addiction reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 2 syntheses or guidelines pooled it, 96 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kristen P MorieDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA.
Sarah W YipDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA; CASAColumbia, New York, NY, USA.
Charla NichDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA.
Karen HunkeleDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA.
Kathleen M CarrollDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA.
Marc N PotenzaDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA; CASAColumbia, New York, NY, USA; Department of Neurobiology, Yale University School of Medicine, New Haven, CT 06510, USA; Child Study Center, Yale University School of Medicine, New Haven, CT 06510, USA; Connecticut Mental Health Center, New Haven, CT 06519, USA.
Yale University · USNational Center on Addiction and Substance Abuse at Columbia University · US

Funding

TSF to enhance treatment of cocaine dependenceP50DA009241 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M. · 1994 to 2018
$40.5M
TRAINING PROGRAM IN CHILDHOOD NEUROPSYCHIATRIC DISORDERST32MH018268 · NIMH · YALE UNIVERSITY · PI Michael H Bloch, MICHAEL J CROWLEY · 1985 to 2026
$11.0M
Neuroimaging Sciences Training ProgramT32DA022975 · NIDA · YALE UNIVERSITY · PI Graeme F Mason, Rajita Sinha · 2007 to 2026
$5.7M
Computer-Based Training in Cognitve Behavioral TherapyR01DA015969 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M. · 2002 to 2015
$2.8M
Computer-Based Training in Cognitve Behavioral TherapyR37DA015969 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M. · 2003 to 2009
$2.6M
Neural mechanisms of CBT in cocaine dependence (Gender Differences Supplement)R01DA035058 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M., POTENZA, MARC N · 2013 to 2016
$2.3M
Neural mechanisms of galantamine treatment for cocaine dependenceK01DA039299 · NIDA · YALE UNIVERSITY · PI YIP, SARAH · 2016 to 2020
$905k
NIDA NIH HHS K01 DA039299NIDA NIH HHS P50 DA009241NIDA NIH HHS R01 DA015969NIDA NIH HHS R01 DA035058NIDA NIH HHS R37 DA015969NIDA NIH HHS T32 DA022975NIMH NIH HHS T32 MH018268United States NIDA
6 · The paper itself

Abstract

Alexithymia, characterized by impairments in emotional awareness, is common among individuals with substance use disorders. Research on alexithymia suggests that it is a trait that may contribute to substance dependence. This paper will review alexithymia as it relates to substance use and substance use disorders, considering its potential role in the maintenance and treatment of these disorders. We will then describe how neural correlates associated with alexithymia may shed light on how alexithymia relates to addiction. Finally, we present preliminary fMRI data that examines how alexithymia may relate to the neurobiological correlates of reward/loss processing in individuals with cocaine dependence. While preliminary, these findings suggest a role of alexithymia in reward anticipation in cocaine-dependent individuals.

Indexed as

AddictionAlexithymiaEmotionfMRIReward processingSubstance abuse

Identifiers

PMID27695665
PMCPMC5040368
OpenAlexW2313268794

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.