Evidence map›Paper›PMID 27695625›Full record

ArticleWebmedCentral2010

Vascular Endothelial Growth Factor Increases Endothelial Nitric Oxide Synthase Transcription In Huvec Cells.

Esther Koai, Tibisay Rincon Rios, John Edwards

Open access · hybridAbstract read
In one paragraph

Article in WebmedCentral, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Esther Koai
Tibisay Rincon Rios
John Edwards
New York Medical College · US

Funding

VASCULAR REGULATION BY FLOW VELOCITY/ENDOTHELIUMP01HL043023 · NHLBI · NEW YORK MEDICAL COLLEGE · PI KALEY, GABOR · 1991 to 2011
$19.5M
EXPANDING FRONTIERS:INTEGRATING INQUIRY, EQUITY, &TECHR25RR015251 · NCRR · AMERICAN PHYSIOLOGICAL SOCIETY · PI MATYAS, MARSHA LAKES · 2000 to 2002
$858k
Doxorubicin-induced cardiac progenitor cell death is antecedent to heart failure.R03HD065551 · NICHD · NEW YORK MEDICAL COLLEGE · PI EDWARDS, JOHN G · 2010 to 2010
$80k
NCRR NIH HHS R25 RR015251NHLBI NIH HHS P01 HL043023NICHD NIH HHS R03 HD065551
6 · The paper itself

Abstract

Although it is known that VEGF increases eNOS protein, the mechanisms responsible remain unclear. To determine if VEGF alters eNOS transcription, human umbilical vein endothelial cells were transfected with reporters under the control of the eNOS promoter and stimulated with VEGF

Indexed as

Endothelial cellseNOSHUVECTranscriptionVEGF

Identifiers

PMID27695625
PMCPMC5040215
OpenAlexW2552538065

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.