ArticleInternational journal of chronic obstructive pulmonary disease2016
Differences in physical activity according to mMRC grade in patients with COPD.
Article in International journal of chronic obstructive pulmonary disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07415746 (Functional Assessment and Pulmonary Rehabilitation), which is not on this map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Functional Assessment and Pulmonary Rehabilitation: Challenges and Perspectives for Comprehensive Care
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between impairment of lung function and risk of anxiety and depression in patients with chronic obstructive pulmonary disease-a systematic review.Systematic reviews · 2024Pooled it
- A Non-Interventional, Cross-Sectional Study to Evaluate Factors Relating to Daily Step Counts and Physical Activity in Japanese Patients with Chronic Obstructive Pulmonary Disease: STEP COPD.International journal of chronic obstructive pulmonary disease · 2020Trial
- Consequences of chronic kidney disease in chronic obstructive pulmonary disease.Respiratory research · 2019Trial
- Prevalence of blood eosinophilia and its impact on lung functions in stable chronic obstructive pulmonary disease patients.Lung India : official organ of Indian Chest Society · 2026Article
- Loneliness in Chronic Obstructive Pulmonary Disease: A Multidimensional Determinant of Clinical Outcomes and Disease Management.Journal of clinical medicine · 2026Review
- People with chronic obstructive pulmonary disease and exercise behaviour: a scoping review using the CFIR framework.BMC pulmonary medicine · 2026Article
- Integration of patient-reported outcomes and myokine profiling for the detection of physical inactivity in COPD: an exploratory multicentre study.Scientific reports · 2026Article
- Multifactorial Determinants of Refractory Breathlessness in COPD: Development of the Refractory Breathlessness Score for Risk Stratification.International journal of chronic obstructive pulmonary disease · 2026Article
- The Impact of Metabolic Syndrome on the Outcomes of Rehabilitation in Post-COVID-19 Patients.Journal of clinical medicine · 2025Article
- Emotional state in patients after COVID-19 in relation to comprehensive rehabilitation, Brain-Derived neurotrophic factor, Irisin levels, and selected clinical factors.Scientific reports · 2025Article
- Factors Influencing Compliance with Pulmonary Rehabilitation in Patients with Stable COPD: a Cross Sectional Study.International journal of chronic obstructive pulmonary disease · 2025Article
- Article
- Extracellular Water Ratio and Phase Angle as Predictors of Exacerbation in Chronic Obstructive Pulmonary Disease.Advances in respiratory medicine · 2024Article
- Prevalence and clinical characteristics of Sarcopenia in older adult patients with stable chronic obstructive pulmonary disease: a cross-sectional and follow-up study.BMC pulmonary medicine · 2024Article
- The Significance of Selected Myokines in Predicting the Length of Rehabilitation of Patients after COVID-19 Infection.Biomedicines · 2024Article
- The Impact of Comprehensive Rehabilitation on the Exercise Capacity of Patients after COVID-19.Advances in respiratory medicine · 2023Article
- Predictors of Quality-of-Life Improvement at Different Minimum Clinically Important Difference Values in Patients with Chronic Obstructive Pulmonary Disease after Climatic Rehabilitation Treatment.Life (Basel, Switzerland) · 2023Article
- Computed Tomography Lung Density Analysis: An Imaging Biomarker Predicting Physical Inactivity in Chronic Obstructive Pulmonary Disease: A Pilot Study.Journal of clinical medicine · 2023Article
- An Algorithm to Classify Real-World Ambulatory Status From a Wearable Device Using Multimodal and Demographically Diverse Data: Validation Study.JMIR biomedical engineering · 2023Article
- Short-Term Benefits of Smoking Cessation Improve Respiratory Function and Metabolism in Smokers.International journal of chronic obstructive pulmonary disease · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPhysical activity (PA) is impaired from the early stages of COPD, is associated with a worsening of disease prognosis, and causes COPD patients to restrict their daily activities in order to avoid breathlessness. The development of a simple tool to estimate physical activity level (PAL) could be useful for the management of COPD.
objectivesWe investigated the differences in PA according to the modified Medical Research Council (mMRC) grade in patients with COPD.
methodsA cross-sectional study was performed on stable outpatients with COPD. PA was measured for 2 weeks using a triaxial accelerometer, and dyspnea grade was evaluated in all patients using the mMRC scale.
resultsNinety-eight patients were recruited. Significant differences in PA duration were observed at all intensities according to the mMRC grade. Despite treatment with controller medications, 59.2% of COPD patients had low PAL, which was <1.5 metabolic equivalents multiplied by hour per day. COPD patients with an mMRC grade ≥2, which was the most balanced cutoff point in the receiver operating characteristic curve, showed a higher reduction rate of PAL (80.0% at mMRC grade 2, 71.4% at mMRC grade 3, and 100% at mMRC grade 4).
conclusionPA differed according to the mMRC grade, and mMRC grade ≥2 could predict a low PAL. Therefore, assessment of breathlessness by the mMRC questionnaire would be useful to stratify the risks of reduced PA in COPD.
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