SynthesisScientific reports2016
Default mode network and frontolimbic gray matter abnormalities in patients with borderline personality disorder: A voxel-based meta-analysis.
Synthesis in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Inhibitory control deficits in borderline personality disorder: a meta-analysis of stop-signal and Go/No-Go tasks.Psychological medicine · 2025Pooled it
- Trial
- Analysis of brain volumetry and functional connectivity during resting state in patients with borderline personality disorder.European archives of psychiatry and clinical neuroscience · 2026Article
- Mapping emotion-modulated inhibitory control in borderline personality features: a dimensional approach using the emotional Go/No-Go task with EEG.Borderline personality disorder and emotion dysregulation · 2025Article
- Neural Correlates of Social Exclusion and Childhood Trauma in Borderline Personality Disorder.Cureus · 2025Article
- Brain Structural Correlates of EEG Network Hyperexcitability, Symptom Severity, Attention, and Memory in Borderline Personality Disorder.Brain sciences · 2025Article
- Neurobiological correlates of personality dimensions in borderline personality disorder using graph analysis of functional connectivity.Scientific reports · 2025Article
- Gray and white matter alterations in Obsessive-Compulsive Personality Disorder: a data fusion machine learning approach.Frontiers in human neuroscience · 2025Article
- Altered gray matter volume and functional connectivity in adolescent borderline personality disorder with non-suicidal self-injury behavior.European child & adolescent psychiatry · 2024Article
- Alternation in functional connectivity within default mode network after psychodynamic psychotherapy in borderline personality disorder.Annals of general psychiatry · 2023Article
- Altered cortical thickness and emotional dysregulation in adolescents with borderline personality disorder.European journal of psychotraumatology · 2023Article
- Ventral Attention Network Correlates With High Traits of Emotion Dysregulation in Community Women - A Resting-State EEG Study.Frontiers in human neuroscience · 2022Article
- Brain responses to social feedback in internalizing disorders: A comprehensive review.Neuroscience and biobehavioral reviews · 2020Review
- Borderline Personality Traits Are Not Correlated With Brain Structure in Two Large Samples.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2020Article
- Brain structure and symptom dimensions in borderline personality disorder.European psychiatry : the journal of the Association of European Psychiatrists · 2020Article
- Functional Connectivity Density, Local Brain Spontaneous Activity, and Their Coupling Strengths in Patients With Borderline Personality Disorder.Frontiers in psychiatry · 2018Article
- Altered regional homogeneity and its association with cognitive function in adolescents with borderline personality disorder.Journal of psychiatry & neuroscience : JPNArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Specific frontolimbic abnormalities are hypothesized to underlie the etiology of borderline personality disorder (BPD). However, findings from neuroimaging studies were inconsistent. In the current study, we aimed to provide a complete overview of cerebral microstructural alterations in gray matter (GM) of BPD patients. A total of 11 studies were enrolled, comprising 275 BPD patients and 290 healthy controls (HCs). A meta-analysis was conduct to quantitatively estimate regional GM abnormalities in BPD patients using the seed-based d mapping (SDM). Meta-regression was also conducted. Compared with HCs, the BPD patients exhibited increased GM mainly in bilateral supplementary motor area extending to right posterior cingulated cortex (PCC) and bilateral primary motor cortex, right middle frontal gyrus (MFG), and the bilateral precuneus extending to bilateral PCC. Decreased GM was identified in bilateral middle temporal gyri, right inferior frontal gyrus extending to right insular, left hippocampus and left superior frontal gyrus extending to left medial orbitofrontal cortex. The mean age of BPD patients were found nagativly associated with GM alterations in right MFG. Our findings suggested that BPD patients have significantly GM abnormalities in the default mode network and frontolimbic circuit. Our results provided further evidences in elucidating the underline neural mechanisms of BPD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.