ArticleMedical principles and practice : international journal of the Kuwait University, Health Science Centre2017
Assessment of Uric Acid Level in the Saliva of Patients with Oral Lichen Planus.
Article in Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Systematic Review and Meta-Analysis of Oxidative Stress and Antioxidant Markers in Oral Lichen Planus.Oxidative medicine and cellular longevity · 2021Pooled it
- Caries experience, periodontal disease and salivary antioxidants as biomarkers of cardiometabolic syndrome among hospital attendees in a Nigerian suburban setting.BMC oral health · 2025Observational
- Study on the potential links between clinical features of oral lichenoid mucositis and systemic diseases.BMC oral health · 2025Article
- Isolation and Characterization of Highly Active Uricase fromPolish journal of microbiology · 2025Article
- MRSL: a causal network pruning algorithm based on GWAS summary data.Briefings in bioinformatics · 2024Article
- Evaluation of the salivary level of glutathione reductase, catalase and free thiol in patients with oral lichen planus.BMC oral health · 2023Article
- Purine Metabolism Dysfunctions: Experimental Methods of Detection and Diagnostic Potential.International journal of molecular sciences · 2023Review
- Article
- Novel Portable Sensing System with Integrated Multifunctionality for Accurate Detection of Salivary Uric Acid.Biosensors · 2021Article
- Salivary Biomarkers and Their Correlation with Pain and Stress in Patients with Burning Mouth Syndrome.Journal of clinical medicine · 2020Article
- Effects of TiOInternational journal of nanomedicine · 2020Article
- The Relationship between the Concentration of Salivary Tyrosine and Antioxidants in Patients with Oral Lichen Planus.Oxidative medicine and cellular longevity · 2019Article
- The validity, stability, and utility of measuring uric acid in saliva.Biomarkers in medicine · 2018Article
- Physiological functions and pathogenic potential of uric acid: A review.Journal of advanced research · 2017Review
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to evaluate the level of uric acid (UA) in saliva, which is considered to be an antioxidant defense biomarker against oxidative stress in patients with oral lichen planus (OLP). SUBJECTS AND
methodsIn this case-control study, 25 OLP patients were included. The reticular form of OLP was verified by a clinical examination with Wickham striae, and other types (erosive, atrophic, ulcerative) were confirmed by histopathological assessment. Thirty healthy individuals matched for age and gender were selected as the control group. In both groups, the Navazesh technique was used to collect the unstimulated saliva. Then, the amount of UA was measured using a Cobas Mira autoanalyzer with a wavelength of 546 nm. The Student t test was used to analyze the data assuming a significance level at <0.05.
resultsOf the 25 patients, the most common type of OLP was erosive (n = 11, 44%), and the most common site of OLP was seen as bilateral in the buccal mucosa (n = 12, 48%). The mean level of salivary UA was significantly lower in the patients with OLP (2.10 ± 0.19 mg/dL) in comparison with the control group (4.80 ± 0.29 mg/dL; p < 0.001).
conclusionIn this study, OLP was associated with a decrease in UA levels in the saliva. Salivary UA as a biomarker could be used for monitoring and treating OLP.
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