Evidence map›Paper›PMID 27694495›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2016

CD4-Transgenic Zebrafish Reveal Tissue-Resident Th2- and Regulatory T Cell-like Populations and Diverse Mononuclear Phagocytes.

Christopher T Dee, Raghavendar T Nagaraju, Emmanouil I Athanasiadis, Caroline Gray, Laura Fernandez Del Ama, Simon A Johnston, Christopher J Secombes, Ana Cvejic, Adam F L Hurlstone

Open access · hybridAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
9.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 148 citations in OpenAlex.

  1. Article
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  3. Review
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  5. Article
  6. Zebrafish as a Model for Translational Immuno-Oncology.Journal of personalized medicine · 2025
    Review
  7. Article
  8. Generation of IgMScientific reports · 2025
    Article
  9. Current research in parasitology & vector-borne diseases · 2025
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Macrophage transplantation rescues RNASET2-deficient leukodystrophy by replacing deficient microglia in a zebrafish model.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Christopher T DeeFaculty of Life Sciences, The University of Manchester, Manchester M13 9PT, United Kingdom.ORCID 0000-0002-0460-4309
Raghavendar T NagarajuFaculty of Life Sciences, The University of Manchester, Manchester M13 9PT, United Kingdom.ORCID 0000-0002-6891-5181
Emmanouil I AthanasiadisWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, United Kingdom.ORCID 0000-0002-2771-5562
Caroline GrayDepartment of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield S10 2RX, United Kingdom.
Laura Fernandez Del AmaFaculty of Life Sciences, The University of Manchester, Manchester M13 9PT, United Kingdom.
Simon A JohnstonDepartment of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield S10 2RX, United Kingdom.
Christopher J SecombesScottish Fish Immunology Research Centre, School of Biological Sciences, University of Aberdeen, Aberdeen AB24 3UU, United Kingdom.ORCID 0000-0001-8781-176X
Ana CvejicWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, United Kingdom; adam.hurlstone@manchester.ac.uk as889@cam.ac.uk.ORCID 0000-0003-3204-9311
Adam F L HurlstoneFaculty of Life Sciences, The University of Manchester, Manchester M13 9PT, United Kingdom; adam.hurlstone@manchester.ac.uk as889@cam.ac.uk.ORCID 0000-0001-5260-9457
University of Manchester · GBUniversity of Cambridge · GBUniversity of Sheffield · GBUniversity of Aberdeen · GB

Funding

Biotechnology and Biological Sciences Research Council BB/L007401/1Cancer Research UK 14953Cancer Research UK A14953European Research Council 282059Medical Research Council MC_PC_12009Medical Research Council MR/J009156/1Medical Research Council MR/L011840/1Wellcome Trust
6 · The paper itself

Abstract

CD4

Indexed as

AnimalsAnimals, Genetically ModifiedCell DifferentiationCells, CulturedFish DiseasesGillsInterleukin-13Interleukin-4Intestinal MucosaMacrophagesMammalsMelanomaMononuclear Phagocyte SystemNeoplasms, ExperimentalTh2 CellsT-Lymphocytes, RegulatoryInterleukin-13Interleukin-4

Identifiers

PMID27694495
PMCPMC5073357
OpenAlexW2527517251

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.