ArticleGenome biology and evolution2017
Genomic Survey of a Hyperparasitic Microsporidian Amphiamblys sp. (Metchnikovellidae).
Article in Genome biology and evolution, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Comprehensive analysis of small GTPases in Microsporidia reveals new extremes in eukaryotic cell biology.BMC biology · 2026Article
- Dollo Parsimony Overestimates Ancestral Gene Content Reconstructions.Genome biology and evolution · 2024Article
- MicroAnnot: A Dedicated Workflow for Accurate Microsporidian Genome Annotation.International journal of molecular sciences · 2024Article
- Ssn6 Interacts with Polar Tube Protein 2 and Transcriptional Repressor for RNA Polymerase II: Insight into Its Involvement in the Biological Process of MicrosporidiumJournal of fungi (Basel, Switzerland) · 2023Article
- Diversity, Distribution, and Development of Hyperparasitic Microsporidia in Gregarines within One Super-Host.Microorganisms · 2023Review
- Intraspecific genetic diversity of the fish-infecting microsporidian parasiteFrontiers in microbiology · 2023Article
- Heterologous Expressed NbSWP12 from MicrosporidiaJournal of fungi (Basel, Switzerland) · 2022Article
- Adaptation to genome decay in the structure of the smallest eukaryotic ribosome.Nature communications · 2022Article
- Microsporidia, a Highly Adaptive Organism and Its Host Expansion to Humans.Frontiers in cellular and infection microbiology · 2022Review
- Insights into Microsporidia Evolution from Early Diverging Microsporidia.Experientia supplementum (2012) · 2022Article
- Comparative Genomics of Microsporidia.Experientia supplementum (2012) · 2022Article
- Analysis of Fungal Genomes Reveals Commonalities of Intron Gain or Loss and Functions in Intron-Poor Species.Molecular biology and evolution · 2021Article
- Phylogenomics of a new fungal phylum reveals multiple waves of reductive evolution across Holomycota.Nature communications · 2021Article
- Molecular phylogeny and new light microscopic data ofParasitology · 2021Article
- Evolutionary relationships of Metchnikovella dogieli Paskerova et al., 2016 (Microsporidia: Metchnikovellidae) revealed by multigene phylogenetic analysis.Parasitology research · 2021Article
- A new method of metabarcoding Microsporidia and their hosts reveals high levels of microsporidian infections in mosquitoes (Culicidae).Molecular ecology resources · 2020Article
- The first case of microsporidiosis inParasitology · 2020Article
- Energy metabolism and its evolution in Microsporidia and allied taxa.Parasitology research · 2020Review
- SCGid: a consensus approach to contig filtering and genome prediction from single-cell sequencing libraries of uncultured eukaryotes.Bioinformatics (Oxford, England) · 2020Article
- Evolution of microsporidia: An extremely successful group of eukaryotic intracellular parasites.PLoS pathogens · 2020Article
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3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Metchnikovellidae are a group of unusual microsporidians that lack some of the defining ultrastructural features characteristic of derived Microsporidia and are thought to be one of their earliest-branching lineages. The basal position of metchnikovellids was never confirmed by molecular phylogeny in published research, and thus far no genomic data for this group were available. In this work, we obtain a partial genome of metchnikovellid Amphiamblys sp. using multiple displacement amplification, next-generation sequencing, and metagenomic binning approaches. The partial genome, which we estimate to be close to 90% complete, displays genome compaction on par with gene-dense microsporidian genomes, but contains an unusual repertoire of unique repeat elements. Phylogenetic analyses of multigene datasets place Amphiamblys sp. as the first branch of the microsporidian lineage following the divergence of a mitochondriate microsporidian Mitosporidium. We find evidence for a mitochondrial remnant presumably functionally equivalent to a mitosome in Amphiamblys sp. and the common enzymatic complement for microsporidian anaerobic metabolism. Comparative genomic analyses identify the conservation of components for clathrin vesicle formation as one of the key features distinguishing the metchnikovellid from its highly derived relatives. The presented data confirm the notion of Metchnikovellidae as a less derived microsporidian group, and provide an additional stepping stone for reconstruction of an evolutionary transition from the early diverging parasitic fungi to derived Microsporidia.
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