Evidence map›Paper›PMID 27694439›Full record

ArticleThe Journal of biological chemistry2016

Mechanisms of Insertion of dCTP and dTTP Opposite the DNA Lesion O6-Methyl-2'-deoxyguanosine by Human DNA Polymerase η.

Amitraj Patra, Qianqian Zhang, F Peter Guengerich, Martin Egli

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Replication Bypass of theBiochemistry · 2024
    Article
  7. Review
  8. Conformation and Pairing Properties of anChemical research in toxicology · 2022
    Article
  9. Deaminated purine bypass by DNA polymerase η.The Biochemical journal · 2021
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Amitraj PatraFrom the Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146.
Qianqian ZhangFrom the Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146.
F Peter GuengerichFrom the Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146 f.guengerich@vanderbilt.edu.
Martin EgliFrom the Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146 martin.egli@vanderbilt.edu.
Vanderbilt University · US

Funding

Synthetic Approaches to Carcinogen-Linked OligonucleotidesP01CA160032 · NCI · VANDERBILT UNIVERSITY · PI STONE, MICHAEL P · 2012 to 2022
$14.0M
BIOACTIVATION OF HALOGENATED HYDROCARBONSR01ES010546 · NIEHS · VANDERBILT UNIVERSITY · PI GUENGERICH, F PETER · 2001 to 2020
$8.1M
POLYMERASE INTERACTIONS WITH CARCINOGEN MODIFIED DNAR01ES010375 · NIEHS · VANDERBILT UNIVERSITY · PI GUENGERICH, F PETER · 2000 to 2014
$5.9M
NCI NIH HHS P01 CA160032NIEHS NIH HHS R01 ES010375NIEHS NIH HHS R01 ES010546
6 · The paper itself

Abstract

O

Indexed as

Bacterial ProteinsCrystallography, X-RayDeoxycytosine NucleotidesDNADNA-Directed DNA PolymeraseDNA Polymerase betaHumansSulfolobus solfataricusThymine Nucleotides2'-deoxycytidine 5'-triphosphateBacterial ProteinsDeoxycytosine NucleotidesDNADNA-Directed DNA PolymeraseDNA Polymerase betaPOLN protein, humanthymidine 5'-triphosphateThymine NucleotidesDNA damageDNA polymeraseenzyme kineticsmass spectrometry (MS)X-ray crystallography

Identifiers

PMID27694439
PMCPMC5104950
OpenAlexW2523815963

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.