Evidence map›Paper›PMID 27694280›Full record

SynthesisPediatrics2016

Patterns of Comorbidity Among Girls With ADHD: A Meta-analysis.

Irene Tung, James J Li, Jocelyn I Meza, Kristen L Jezior, Jessica S V Kianmahd, Patrick G Hentschel, Paul M O'Neil, Steve S Lee

Registry-linked trialOpen access · greenAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06146595 (Prevalence Study of Attention Deficit Hyperactivity Disorder and Its Comorbidities Among a Sample of Primary School Students in New Valley Governorate), which is not on this map. Cited by 43 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 4 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06146595 unknown statusnot on this mapstarted 2024, after this paper: background citation

Prevalence Study of Attention Deficit Hyperactivity Disorder and Its Comorbidities Among a Sample of Primary School Students in New Valley Governorate

Typeobservational_patient_registrySponsorAssiut UniversityRan2024 to 2025Enrolled200ConditionsADHD
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 4 syntheses or guidelines pooled it, 106 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Pooled it
  5. Article
  6. Article
  7. Observational
  8. Oppositional Defiant Disorder in Autism and ADHD.Journal of autism and developmental disorders · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. The SASOP/PsychMg child and adolescent attention-deficit/hyperactivity disorder guidelines.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2025
    Article
  15. Training of Awareness in ADHD: Leveraging Metacognition.Journal of psychiatry and brain science · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. A Gender-Based Point of View in Pediatric Neurology.Journal of personalized medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Irene TungDepartment of Psychology, University of California, Los Angeles, Los Angeles, California.
James J LiDepartment of Psychology, University of Wisconsin, Madison, Wisconsin; and.
Jocelyn I MezaDepartment of Psychology, University of California, Berkeley, Berkeley, California.
Kristen L JeziorDepartment of Psychology, University of California, Los Angeles, Los Angeles, California.
Jessica S V KianmahdDepartment of Psychology, University of California, Los Angeles, Los Angeles, California.
Patrick G HentschelDepartment of Psychology, University of California, Los Angeles, Los Angeles, California.
Paul M O'NeilDepartment of Psychology, University of California, Los Angeles, Los Angeles, California.
Steve S LeeDepartment of Psychology, University of California, Los Angeles, Los Angeles, California; stevelee@psych.ucla.edu.
University of California, Los Angeles · USUniversity of California, Berkeley · USUniversity of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextAlthough children with attention-deficit/hyperactivity disorder (ADHD) are at elevated risk for comorbid psychopathology, the clinical correlates of ADHD in girls are far less understood relative to boys, despite ADHD being one of the most common childhood disorders in girls.

objectiveTo meta-analytically summarize rates of comorbid internalizing (anxiety, depression) and externalizing (oppositional defiant disorder [ODD], conduct disorder [CD]) psychopathology among girls with and without ADHD. DATA SOURCES: Literature searches (PubMed, Google Scholar) identified published studies examining comorbid psychopathology in girls with and without ADHD. STUDY SELECTION: Eighteen studies (1997 participants) met inclusion criteria and had sufficient data for the meta-analysis. DATA EXTRACTION: Odds ratios for each comorbid disorder were calculated from available data. Demographic (eg, age, race/ethnicity) and study characteristics (eg, referral source, diagnostic method) were also coded.

resultsCompared with girls without ADHD, girls with ADHD were significantly more likely to meet Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria for each comorbid disorder assessed. Relative odds were higher for externalizing (ODD: 5.6×; CD: 9.4×) relative to internalizing disorders (anxiety: 3.2×; depression: 4.2×). Meta-regression revealed larger effect sizes of ADHD on anxiety for studies using multiple diagnostic methods, featuring younger children, and including clinic-referred (versus community-referred) girls; the effect of ADHD on ODD varied based on diagnostic informant. LIMITATIONS: Findings were derived from cross-sectional studies, precluding causal inferences.

conclusionsGirls with ADHD frequently exhibit comorbid externalizing and internalizing disorders. We discuss future research priorities and consider intervention implications for ADHD and comorbid psychopathology in girls.

Indexed as

AdolescentAttention Deficit Disorder with HyperactivityChildComorbidityDiagnostic and Statistical Manual of Mental DisordersFemaleHumansMental DisordersPsychopathology

Identifiers

PMID27694280
PMCPMC9923580
OpenAlexW2522647067

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.