Evidence map›Paper›PMID 27694177›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2016

Evaluation of Castration-Resistant Prostate Cancer with Androgen Receptor-Axis Imaging.

Neeta Pandit-Taskar, Darren R Veach, Josef J Fox, Howard I Scher, Michael J Morris, Steven M Larson

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Multimodality Imaging of Prostate Cancer.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2019
    Review
  6. Fluorine-18 Labeled Fluorofuranylnorprogesterone ([Molecules (Basel, Switzerland) · 2019
    Article
  7. Article
  8. Review
  9. Trends in oncologic hybrid imaging.European journal of hybrid imaging · 2018
    Review
  10. Review
  11. Article
  12. Radiotheranostics in Prostate Cancer: Introduction and Overview.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Neeta Pandit-TaskarDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York; and.
Darren R VeachDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York; and.
Josef J FoxDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York; and.
Howard I ScherDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Michael J MorrisDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Steven M LarsonDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York; and larsons@mskcc.org.
Memorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Castration-resistant prostate cancer (CRPC) is the lethal form of prostate cancer, and more than 26,000 men will die from this disease in 2016. The pathophysiology of CRPC is clearly multifactorial, but most often, androgen receptor (AR) upregulation is associated with its earliest beginnings and the AR increase is part of the multimolecular complex including downstream effector proteins linked to AR (AR-axis) responsible for rapid proliferation and malignant features of the malignant cell. In both animal models and patients, glycolysis (Warburg effect) is also an early manifestation of CRPC transformation. At Memorial Sloan Kettering Cancer Center, we have focused our energies on imaging studies of the AR-axis in CRPC, using

Indexed as

Positron Emission Tomography Computed TomographyBiomarkers, TumorDihydrotestosteroneEvidence-Based MedicineHumansImage EnhancementMaleMolecular ImagingNeoplasm StagingProstatic NeoplasmsProstatic Neoplasms, Castration-ResistantRadiopharmaceuticalsReceptors, Androgen16-fluorodihydrotestosteroneBiomarkers, TumorDihydrotestosteroneRadiopharmaceuticalsReceptors, Androgenandrogen receptor–axis imagingcastration-resistant prostate cancerCRPCmolecular imagingoncology: GUradioimmunoimaging

Identifiers

PMID27694177
PMCPMC12530359
OpenAlexW2524641066

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.