Evidence map›Paper›PMID 27694044›Full record

ArticleEnvironmental research2016

Physical activity, black carbon exposure and airway inflammation in an urban adolescent cohort.

Stephanie Lovinsky-Desir, Kyung Hwa Jung, Andrew G Rundle, Lori A Hoepner, Joshua B Bautista, Frederica P Perera, Steven N Chillrud, Matthew S Perzanowski, Rachel L Miller

Open access · greenAbstract read
In one paragraph

Article in Environmental research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Pooled it
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  8. Self-Reported Physical Activity and Asthma Risk in Children.The journal of allergy and clinical immunology. In practice · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Stephanie Lovinsky-DesirDivision of Pediatric Pulmonology, Department of Pediatrics, College of Physicians and Surgeons, Columbia University, 3959 Broadway CHC-745, New York, NY 10032, United States. Electronic address: sl3230@cumc.columbia.edu.
Kyung Hwa JungDivision of Pulmonary, Allergy and Critical Care of Medicine, Department of Medicine, College of Physicians and Surgeons, Columbia University, PH8E-101, 630 W. 168S., New York, NY 10032, United States.
Andrew G RundleDepartment of Epidemiology, Mailman School of Public Health, Columbia University, 722 W. 168S., New York, NY 10032, United States.
Lori A HoepnerDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 722 W. 168S., New York, NY 10032, United States; Department of Environmental and Occupational Health Sciences, State University of New York, Downstate School of Public Health, Box 43, 450 Clarkson Avenue, Brooklyn, NY 11203, United States.
Joshua B BautistaDivision of Pulmonary, Allergy and Critical Care of Medicine, Department of Medicine, College of Physicians and Surgeons, Columbia University, PH8E-101, 630 W. 168S., New York, NY 10032, United States.
Frederica P PereraDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 722 W. 168S., New York, NY 10032, United States.
Steven N ChillrudLamont-Doherty Earth Observatory, Columbia University, 61 Rt, 9W Palisades, New York 10964, United States.
Matthew S PerzanowskiDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 722 W. 168S., New York, NY 10032, United States.
Rachel L MillerDivision of Pulmonary, Allergy and Critical Care of Medicine, Department of Medicine, College of Physicians and Surgeons, Columbia University, PH8E-101, 630 W. 168S., New York, NY 10032, United States; Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 722 W. 168S., New York, NY 10032, United States; Division of Pediatric Allergy, Immunology, and Rheumatology, Department of Pediatrics, College of Physicians and Surgeons, Columbia University, PH8E-101, 630 W. 168 St., New York, NY 10032, United States.
Columbia University · USLamont-Doherty Earth Observatory · USSUNY Downstate Health Sciences University · US

Funding

True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
The Columbia Center for Children's Environmental HealthP01ES009600 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CHAMPAGNE, FRANCES A. · 1999 to 2014
$11.2M
Urban Diesel Exposure and Inner City AsthmaR01ES013163 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MILLER, RACHEL L · 2005 to 2016
$6.5M
Clinical and Translational Science AwardKL2TR000081 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$3.3M
NCATS NIH HHS KL2 TR000081NIEHS NIH HHS L40 ES023169NIEHS NIH HHS P01 ES009600NIEHS NIH HHS P30 ES009089NIEHS NIH HHS R01 ES013163
6 · The paper itself

Abstract

objectiveRegular physical activity can improve cardiopulmonary health; however, increased respiratory rates and tidal volumes during activity may increase the effective internal dose of air pollution exposure. Our objective was to investigate the impact of black carbon (BC) measured by personal sampler on the relationship between physical activity and fractional exhaled nitric oxide (FeNO), a marker of airway inflammation. We hypothesized that higher personal BC would attenuate the protective effect of physical activity on airway inflammation.

methodsWe performed a cross-sectional study nested in a birth cohort of African American and Dominican children living in the Bronx and Northern Manhattan, New York City. Children were recruited based on age (target 9-14 year olds) and presence (n=70) or absence (n=59) of current asthma. Children wore wrist mounted accelerometers for 6 days and were classified as 'active' if they had ≥60min of moderate-to-vigorous activity (MVA) each day and 'non-active' if they had <60min of MVA on any given day, based on CDC guidelines. Personal BC measured using a MicroAeth, was assessed during two 24-h periods, at the beginning and end of physical activity assessment. High BC was defined as the upper tertile of BC measured with personal sampler. FeNO measurements were sampled at the beginning and end of the of physical activity assessment.

resultsIn multivariable linear regression models, 'active' children had 25% higher personal BC concentrations (p=0.02) and 20% lower FeNO (p=0.04) compared to 'non-active' children. Among children with high personal BC (n=33), there was no relationship between activity and FeNO (p=1.00). The significant protective relationship between activity and airway inflammation was largely driven by children with lower personal BC (n=96, p=0.04).

conclusionsChildren that live in an urban environment and are physically active on a daily basis have higher personal exposure to BC. High BC offsets the protective relationship between physical activity and airway inflammation.

Indexed as

ExerciseUrban PopulationAdolescentAir PollutantsAsthmaCross-Sectional StudiesFemaleHumansInhalation ExposureMaleMultivariate AnalysisNew York CityRegression AnalysisSootAir PollutantsSootAir pollutionAsthmaExerciseFeNOUrban environment

Identifiers

PMID27694044
PMCPMC5081133
OpenAlexW2524665015

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.